432049-65-5

Upstream product

• 432049-62-2 4-(4-methoxy-phenyl)-2-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 765298-87-1 2-hydroxy-4-(4-methoxy-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Heck arylations of N-acyl-3-pyrroline and N-acyl-1,2,5,6-tetrahydropyridine with aryldiazonium salts. Short syntheses of aryl γ- and δ-lactams, baclofen, homobaclofen and analogues

Heck arylation of N-acyl-3-pyrrolines and an N-acyl-tetrahydropyridine with aryldiazonium tetrafluoroborates under phosphine-free conditions proceeded smoothly to give α-hydroxycarbamates (hemiaminals) or α-alkoxycarbamates which were oxidized to the desi