43212-67-5

Basic information

• Product Name: 1-methoxy-4-[(1E)-4-(4-methoxyphenyl)buta-1,3-dien-1-yl]benzene
• CAS NO: 43212-67-5
• Molecular Formula: C₁₈H₁₈O₂
• Molecular Weight: 266.3343
• Mol File: 43212-67-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 445.2°C at 760 mmHg
• Flash Point: 180.6°C
• Density: 1.077g/cm³
• Vapor Pressure: 1.06E-07mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 1-methoxy-4-[(1E)-4-(4-methoxyphenyl)buta-1,3-dien-1-yl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-[(1E)-4-(4-methoxyphenyl)buta-1,3-dien-1-yl]benzene(43212-67-5)
• EPA Substance Registry System: 1-methoxy-4-[(1E)-4-(4-methoxyphenyl)buta-1,3-dien-1-yl]benzene(43212-67-5)

Safety Data

• Hazardous Substances Data: 43212-67-5(Hazardous Substances Data)

Usage

General Description

1-Methoxy-4-[(1E)-4-(4-methoxyphenyl)buta-1,3-dien-1-yl]benzene, also known as Anethole, is an organic compound with a chemical formula C17H18O. It is a colorless or slightly yellow liquid with a sweet and aromatic odor, commonly found in the essential oils of anise, fennel, and star anise. Anethole has various applications in the food and beverage industry, where it is used as a flavoring agent in products such as candy, gum, and alcoholic beverages. It is also used in the production of perfumes and soaps due to its pleasant aroma. Anethole has been studied for its potential pharmaceutical properties, including antioxidant, antimicrobial, and anti-inflammatory effects. However, it is important to use Anethole in moderation, as excessive consumption or exposure to high concentrations can have toxic effects on the nervous system.

Upstream product

• 150-90-3 sodium succinate 
• 123-11-5 4-methoxy-benzaldehyde 
• 1041465-92-2 potassium 4-bromo styryltrifluoroborate 
• 1963-36-6 4-methoxycinnamaldehyde 
• 17105-65-6 dimethyl 4-methoxybenzylphosphonate 
• 644-97-3 Dichlorophenylphosphine 
• 768-60-5 4-methoxyphenylacetylen 
• 824-94-2 p-methoxybenzyl chloride 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 
• 6303-59-9 (E)-4-(2-bromo-vinyl)-anisole 
• 214907-25-2 (4-methoxystyrene)boronic acid 
• 1614-12-6 1H-1,2,3-benzotriazol-1-amine 
• 832-01-9 methyl p-methoxycinnamate 

Downstream Products

• 16620-11-4 4,5-Di-benzoyl-3,6-di-p-anisylcyclohexen 
• 1170321-13-7 1,4-bis-(4-methoxyphenyl)naphthalene 
• 89148-27-6 4,4’-((1E,3E)-buta-1,3-diene-1,4-diyl)diphenol 
• 16620-14-7 1,2-Di-p-anisoyl-3,6-di-p-anisyl-benzol 
• 16620-12-5 1,2-Di-benzoyl-3,6-di-p-anisyl-benzol 
• 100-09-4 4-methoxybenzoic acid 
• 16620-13-6 4,5-Di-p-anisoyl-3,6-di-p-anisylcyclohexen 

Relevant articles and documents

Copper-Mediated Difunctionalization of Alkenylboronic Acids: Synthesis of ɑ-Imino Ketones

Various ɑ-imino ketones were prepared in good yields through a copper-mediated difunctionalization of alkenylboronic acids with benzotriazolamine in air. Mechanistic studies showed that ɑ-imino ketones formation occurred through an initial copper-mediated coupling reaction to form an enamine, followed by homolysis of the C?Cu bond to produce an ɑ-radical imine, and finally radical oxidation by air. The ɑ-imino ketones were easily converted to various useful scaffolds through further transformations. (Figure presented.).

Cyanuric chloride-dimethylformamide mediated cleavage of cyclopropylcarbinols-synthesis of phenolic antioxidant and construction of a new vinylcyclopropane skeleton

Differently substituted cyclopropylcarbinols underwent ring cleavage with easily accessible cyanuric chloride-N,N-dimethylformamide adduct to produce homoallylic chlorides or dienes depending on the nature and location of the substituents. A mechanistic explanation of the aforesaid observations has been provided. A promising antioxidant compound was prepared following this protocol and studied against Fenton's reagent. This methodology was utilized to construct hitherto unreported vinylcyclopropane frameworks bearing homoallylic chloride and diene moieties.

Reactivity differences between 2,4- and 2,5-disubstituted zirconacyclopentadienes: A highly selective and general approach to 2,4-disubstituted phospholes

Mixtures of 2,4- and 2,5-disubstituted zirconacyclopentadienes were obtained by the reductive dimerisation of terminal alkynes using the Cp 2ZrCl2/lanthanum system. Reactions of dihalophosphines with these mixtures afforded selectively the corresponding 2,4-disubstituted phospholes and 1,4-disubstituted butadienes. A new series of phospholes was characterized by multi-nuclear NMR spectroscopy and X-ray analysis. A possible explanation for the observed selectivity was obtained from X-ray studies and DFT analysis of the intermediate zirconacyclopentadienes. The Royal Society of Chemistry 2013.