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Coumarin, 3,3-(o-chlorobenzylidene)bis(4-hydroxy-), is a chemical compound with the molecular formula C17H12Cl2O4. It is a derivative of coumarin, a naturally occurring organic compound found in plants, and is characterized by the presence of two o-chlorobenzylidene groups connected to the central coumarin structure. COUMARIN, 3,3-(o-CHLOROBENZYLIDENE)BIS(4-HYDROXY- is known for its yellow color and is used in various applications, including as a fluorescent brightening agent in the textile industry and as a reagent in chemical analysis. Its chemical structure provides it with unique properties that make it valuable in these specific fields.

4322-58-1

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4322-58-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4322-58-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,2 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4322-58:
(6*4)+(5*3)+(4*2)+(3*2)+(2*5)+(1*8)=71
71 % 10 = 1
So 4322-58-1 is a valid CAS Registry Number.

4322-58-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(2-chlorophenyl)-(4-hydroxy-2-oxochromen-3-yl)methyl]-4-hydroxychromen-2-one

1.2 Other means of identification

Product number -
Other names T0503-2105

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4322-58-1 SDS

4322-58-1Relevant academic research and scientific papers

Facile and Straightforward Synthesis of Racemic Version of Substituted 3-[3-(2-Hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins: Easy Access to a Series of Biorelevant Warfarin Analogues

Brahmachari, Goutam,Mandal, Mullicka,Karmakar, Indrajit

, p. 451 - 464 (2021/10/19)

The present communication deals with a straightforward, efficient, and green synthesis of a series of racemic version of 3-[3-(2- hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins as biologically interesting warfarin analogues upon decarboxylative hyd

Developing a highly potent anthelmintic: study of catalytic application of l-proline derived aminothiourea in rapid synthesis of biscoumarins and their in vitro anthelmintic essay

Kharrngi, Balamphrang,Dhar, Errini Decruse,Basumatary, Grace,Das, Dharitri,Deka, Ramesh Ch,Yadav, Arun K,Bez, Ghanashyam

, (2021/02/22)

Abstract: Due to serious side effects of benzimidazoles such as apoptosis and mitotic arrest, development of alternative anthelmintic drugs with comparable efficacy to target the acetylcholine receptors of parasites is considered very important to control

Click chemistry-inspired design, synthesis, and molecular docking studies of biscoumarin derivatives using carbon-based acid catalyst

Agarwal, Dinesh K.,Sethiya, Ayushi,Teli, Pankaj,Manhas, Anu,Soni, Jay,Sahiba, Nusrat,Jha, Prakash C.,Agarwal, Shikha,Goyal, Pradeep K.

, p. 3294 - 3309 (2020/07/13)

A green and eco-benign synthesis of biscoumarin derivatives using carbon sulfonic acid, a solid support catalyst has been described. The reaction involved a one-pot two-component reaction of 4-hydroxycoumarin and aldehyde using carbon sulfonic acid involv

The immobilized Ni(II) species on thiourea functionalized copper ferrite: a reusable nanocatalyst for synthesis of biscoumarins under solvent-free conditions

Zeynizadeh, Behzad,Hasanpour Galehban, Morteza,Shokri, Zahra

, p. 1493 - 1505 (2020/02/27)

In this study, nanoparticles of CuFe2O4@SiO2@PTMS@Tu@Ni(II) as the reusable magnetic catalyst were prepared. Synthesis of the Ni(II)–CuFe2O4 system was carried out through a five-step procedure includ

Heterogeneous SO3H@Fe3O4 magnetic nanocatalyst as an efficient and reusable medium for the synthesis of 3,3′-(arylmethylene)-bis-(4-hydroxycoumarin), bis-(indolyl)-methane, and 1,8-dioxo-octahydroxanthene derivatives

Wu, Xiaobo,Peng, Wan-Xi

, p. 2129 - 2148 (2020/06/24)

This work aimed to synthesize a new heterogeneous catalyst (SO3H@Fe3O4 magnetic nanoparticles) and the study of its catalytic behavior in synthesizing 3,3′-(arylmethylene)-bis-(4-hydroxycoumarin), bis-(indolyl)-methane, an

Efficient synthesis of bis-(4-hydroxycoumarin) using sulfanilic acid as recyclable catalyst in water

SADAT-JALALI, Mozhgan,MANAFI, Mohammadreza,HOMAMI, Seyed Saied,GORJI, Banafsheh,MONZAVI, Amirhossein

, p. 473 - 480 (2020/10/06)

A catalytic reaction between aromatic aldehydes and 4- hydroxycoumarin has been developed to form a decent range of functionalized biscoumarin skeletons in excellent yields using sulfanilic acid as reusable catalyst in aqueous media. The catalytic reactio

Fabrication and characterization of the immobilized Cu(II) and Ni(II) species on silica-coated copper ferrite: as novel magnetically reusable nanocatalysts toward synthesis of biscoumarins

Zeynizadeh, Behzad,Sadeghbari, Maryam,Noroozi Pesyan, Nader

, p. 73 - 88 (2019/08/13)

In this study, we have synthesized magnetically nanoparticles (MNPs) of CuFe2O4@SiO2@AAPTMS@Ni(II) and CuFe2O4@SiO2@AAPTMS@Cu(II). The prepared nanocomposite systems were characterized usin

Aluminized Polyborate-catalyzed Environmentally Benign Solvent-free Protocol for the Synthesis of Bis-coumarin Derivatives

Aute, Dilip,Kshirsagar, Akshay,Kadnor, Vijay,Uphade, Bhagwat,Gadhave, Anil

, p. 599 - 605 (2021/01/25)

The present work reports, an efficient application of aluminized polyborate as a mild solid acid catalyst for the multicomponent synthesis of biologically important bis-coumarin derivatives. The one-pot synthesis of bis-coumarins involves domino Knoevenag

Strongly proton exchanged montmorillonite K10 (H+-Mont) as a solid acid catalyst for highly efficient and environmental benign synthesis of biscoumarins via tandem Knoevenagel–Michael reaction

Zeynizadeh, Behzad,Rahmani, Soleiman,Ilkhanizadeh, Siamand

, p. 48 - 56 (2019/05/15)

In this study, synthesis of micro/meso porous acid-activated montmorillonite K10 (H+-Mont) was carried out by the activation of Na+-montmorillonite with HCl (4 M) at the controlled conditions. The prepared H+-Mont clay was

Synthesis of bis-coumarins over acetic acid functionalized poly(4-vinylpyridinum) bromide (APVPB) as a green and efficient catalyst under solvent-free conditions and their biological activity

Noroozizadeh, Ehsan,Moosavi-Zare, Ahmad Reza,Zolfigol, Mohammad Ali,Zarei, Mahmoud,Karamian, Roya,Asadbegy, Mostafa,Yari, Siamak,Farida, Seyed Hamed Moazzami

, p. 471 - 481 (2018/03/29)

Abstract: In this work, acetic acid functionalized poly(4-vinylpyridinum) bromide as a green and reusable catalyst was successfully tested on the synthesis of various bis-coumarins under solvent-free conditions. In addition, antioxidant and anti-inflammat

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