43230-11-1

Basic information

• Product Name: Ethanone, 1-(4-amino-3-methylphenyl)- (9CI)
• Synonyms: Ethanone, 1-(4-amino-3-methylphenyl)- (9CI);1-(4-Amino-3-methyl-phenyl)-ethanone
• CAS NO: 43230-11-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Product Categories: ACETYLGROUP
• Mol File: 43230-11-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 310.9 °C at 760 mmHg
• Flash Point: 141.8 °C
• Appearance: /
• Density: 1.069 g/cm³
• CAS DataBase Reference: Ethanone, 1-(4-amino-3-methylphenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-amino-3-methylphenyl)- (9CI)(43230-11-1)
• EPA Substance Registry System: Ethanone, 1-(4-amino-3-methylphenyl)- (9CI)(43230-11-1)

Safety Data

• Hazardous Substances Data: 43230-11-1(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(4-amino-3-methylphenyl)- (9CI) is a chemical compound with the molecular formula C9H11NO. It is also known by its systematic name 1-(4-Amino-3-methylphenyl)ethan-1-one. Ethanone, 1-(4-amino-3-methylphenyl)- (9CI) belongs to the class of organic compounds known as phenyl-1,2,3-triazoles. Phenyl-1,2,3-triazoles come from a subclass of phenyl-1,2,4-triazoles, which are compounds containing a 1,2,4-triazole moiety that is substituted with a phenyl group. This chemical compound is commonly used in pharmaceutical research as a building block for the synthesis of various pharmaceutical compounds. It has potential applications in the development of new drugs and may be used as an intermediate in the synthesis of pharmaceutical products.

Upstream product

• 108-24-7 acetic anhydride 
• 95-53-4 o-toluidine 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 96784-58-6 4-nitro-3-methylacetophenone 
• 40664-73-1 4'-acetylamino-3'-methyl-acetophenone 
• 75-36-5 acetyl chloride 

Downstream Products

• 37074-40-1 1-(4-bromo-3-methylphenyl)ethan-1-one 
• 1438383-92-6 3-acetyl-10,11-dihydro-5H-benzo[d]naphtho[2,3-b]pyran-8(9H)-one 
• 1438383-89-1 9-bromo-3-(2-bromoacetyl)-10,11-dihydro-5H-benzo[d]naphtho[2,3-b]pyran-8(9H)-one 
• 954371-95-0 methyl 3-(4-acetyl-2-methylphenyl)-2-bromopropionate 
• 40664-73-1 4'-acetylamino-3'-methyl-acetophenone 
• 52107-80-9 1-(4-iodo-3-methyl-phenyl)-ethanone 
• 876-02-8 4-hydroxy-3-methylphenyl methyl ketone 

Relevant articles and documents

Efficient hydrogenation catalyst designing via preferential adsorption sites construction towards active copper

Based on the experimental and DFT calculation results, here for the first time we built preferential adsorption sites for nitroarenes by modification of the supported Cu catalysts surface with 1,10-phenathroline (1,10-phen), by which the yield of aniline via reduction of nitroarene is enhanced three times. Moreover, a macromolecular layer was in-situ generated on supported Cu catalysts to form a stable macromolecule modified supported Cu catalyst, i.e., CuAlOx-M. By applying the CuAlOx-M, a wide variety of nitroarene substrates react smoothly to afford the desired products in up to > 99% yield with > 99% selectivity. The method tolerates a variety of functional groups, including halides, ketone, amide, and C = C bond moieties. The excellent catalytic performance of the CuAlOx-M can be attributed to that the 1,10-phen modification benefits the preferential adsorption of nitrobenzene and slightly weakens adsorption of aniline on the supported nano-Cu surface.

Photo-Fries rearrangement of aryl acetamides: Regioselectivity induced by the aqueous micellar green environment

Photochemical reactions tend to give more than one photoproduct. However, such a reaction can be a powerful synthetic tool when it is possible to conduct it in regioselective conditions yielding a single photoproduct. Water-surfactant solutions as reaction media can be considered as an approach in this context because they show products with different features than those from isotropic solutions. Here we describe results obtained from studying the effect on the prototypical photoreaction, known as the photo-Fries reaction of several substituted acetanilides and α-naphthyl acetamide within surfactant micelles (ionic and non-ionic micelles). This reaction involves homolytic cleavage of a C-N bond to yield a singlet radical pair. The surfactant micelles control the rotational and translational mobility of the radical pair, resulting in noticeable photoproduct selectivity.

METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND, AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND

There is provided a novel intermediate for producing pesticides. A method for producing 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4) and a substituted acetophenone compound of Formula (5) as starting raw materials in an organic solvent or water in the presence or absence of an additive in the presence of a base in a suspended state. A method for producing 1,3-bis(substituted phenyl)-3-substituted-2-propen-2-one compound of Formula (2) comprises dehydrating the compound of Formula (3). A method for producing compound (2) in one step comprises reacting compound (4) and compound (5) to obtain compound (3). Further, a method for producing an isoxazoline compound of Formula (1) comprises reacting compound (2) and a hydroxylamine in an aliphatic or an aromatic hydrocarbon solvent which is optionally substituted by a halogen atom by adding an additive selected from a phase-transfer catalyst, a C1-C6 alcohol and an aprotic polar solvent in the presence of a base and water.