432547-06-3Relevant academic research and scientific papers
Synthesis and glycosidase inhibitory activity of some N-substituted 5a-carba-β-fuco- and β-galactopyranosylamines, and selected derivatives
Ogawa, Seiichiro,Fujieda, Shigeo,Sakata, Yuko,Ishizaki, Masahiro,Hisamatsu, Seiichi,Okazaki, Kensuke,Ooki, Yoriko,Mori, Midori,Itoh, Masayoshi,Korenaga, Takashi
, p. 6569 - 6579 (2007/10/03)
In the course of chemical modification of α-fucosidase inhibitors of 5a-carba-fucopyranosylamine type, an N-dodecyl derivative of the enantiomer 6-deoxy-5a-carba-β-d-galactopyranosylamine demonstrated very strong inhibition of β-galactosidase and β-glucos
Synthesis of an α-fucosidase inhibitor, 5a-carba-β-L-fucopyranosylamine, and fucose-type α- and β-DL-valienamine unsaturated derivatives
Ogawa, Seiichiro,Watanabe, Maiko,Maruyama, Ayako,Hisamatsu, Seiichi
, p. 749 - 752 (2007/10/03)
Discovery of a very potent α-fucosidase inhibitor 5a-carba-α-L-fucopyranosylamine (1) led to preparation of its β-anomer 4 and the respective unsaturated derivatives, fucose-type α- and β-valienamines (5 and 6), in order to elucidate the structure-activit
