4330-24-9

Basic information

• Product Name: 2-furylmethyl 4-methylbenzoate
• Synonyms: 2-furylmethyl 4-methylbenzoate
• CAS NO: 4330-24-9
• Molecular Formula: C₁₃H₁₂O₃
• Molecular Weight: 216.23258
• Mol File: 4330-24-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-furylmethyl 4-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-furylmethyl 4-methylbenzoate(4330-24-9)
• EPA Substance Registry System: 2-furylmethyl 4-methylbenzoate(4330-24-9)

Safety Data

• Hazardous Substances Data: 4330-24-9(Hazardous Substances Data)

Upstream product

• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 67-47-0 5-hydroxymethyl-2-furfuraldehyde 
• 624-31-7 4-tolyl iodide 
• 4301-14-8 acetylenemagnesium bromide 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 22900-10-3 2-deoxy-D-ribose 
• 4330-34-1 methyl 3,5-di-O-toluoyl-2-deoxy-D-ribofuranose 
• 1070990-50-9 4-(Trimethylsilylamino)-7-(trimethylsilyloxy)pteridin 
• 3056-12-0 2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythropentofuranosyl chloride 

Relevant articles and documents

HMF and furfural: Promising platform molecules in rhodium-catalyzed carbonylation reactions for the synthesis of furfuryl esters and tertiary amides

A biomass involved rhodium-catalyzed carbonylative synthesis of furfuryl esters and tertiary amides has been developed. 5-Hydroxymethylfurfural (HMF) was used as both substrate and CO surrogate for the first time in a carbonylation reaction, and both alkyl and aryl iodides were tolerated well to afford the desired furfuryl esters in moderate to good yields. In addition, furfural was also utilized as a CO source for the synthesis of tertiary amides. A variety of tertiary amides were obtained in moderate to excellent yields with good functional groups compatibility. Notably, tertiary amines were used as the amine source through a C[sbnd]N bond cleavage pathway in the absence of additional oxidant.

Convenient preparation of 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

By using acetyl chloride as HCl generator, the procedure for the Hoffer preparation of the α-chloro sugar 4a was significantly improved. The α-configuration of the chloro atom was confirmed by using NOE measurement. Sequential transformation of 4a to the β-anomer and to the furfuryl derivative 6 was studied.

Nucleosides, XXXVI. - Synthesis and Properties of 4-Amino-8-β-D-ribofuranosyl-7(8H)-pteridinone and its 2- and 6-Phenyl Derivatives.

4-Amino-7(8H)-pteridinone (5) and its 2- and 5-phenyl derivatives (6-8) are converted by the Silyl-Hilbert-Johnson method to the corresponding acylated N-8-ribosides (15-18, 23, 24).Deacylation led to the free pteridine nucleosides (19-22, 25) which can b