433283-76-2Relevant academic research and scientific papers
A preliminary approach to nonenolizable β,β-tricarbonyls: Assembly of a hyperevolutin prototype
Young, David G. J.,Zeng, Dongxiang
, p. 3134 - 3137 (2007/10/03)
A synthetic approach to the hyperevolutin A acylated phloroglucinol ring system is described. Thus, intramolecular allene-nitrile oxide cycloaddition of 10 was used to construct the bicyclic framework and vicinal quaternary centers in cycloadduct 20 in the key bond-forming step. Treatment of 20 with Raney nickel and hydrogen gas produced primary enamine 21 which contains a nonenolizable β,β-tricarbonyl group in latent form.
