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PTH-L-PROLINE, also known as parathyroid hormone-related protein (PTHrP), is a protein fragment that plays a vital role in calcium homeostasis and bone metabolism. It is produced by various tissues in the body, including the parathyroid gland, bone, and placenta. PTH-L-PROLINE acts as a hormone and functions similarly to parathyroid hormone by regulating calcium levels in the blood and promoting bone development and remodeling. It also has diverse effects on various physiological processes, such as cell proliferation, differentiation, and apoptosis. PTH-L-PROLINE has been investigated for its potential therapeutic applications in bone disorders, cancer, and other diseases related to calcium metabolism. Its role in regulating calcium levels makes it a valuable target for understanding and treating a range of conditions related to bone and mineral homeostasis.

4333-21-5

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4333-21-5 Usage

Uses

Used in Pharmaceutical Industry:
PTH-L-PROLINE is used as a therapeutic agent for bone disorders, such as osteoporosis and Paget's disease, due to its ability to regulate calcium levels and promote bone development and remodeling.
Used in Oncology:
PTH-L-PROLINE is used as a potential therapeutic agent for cancer treatment, particularly in bone metastasis, as it can regulate calcium levels and affect cell proliferation, differentiation, and apoptosis.
Used in Research:
PTH-L-PROLINE is used as a research tool to study the molecular mechanisms underlying calcium homeostasis, bone metabolism, and the physiological processes of cell proliferation, differentiation, and apoptosis. This helps in understanding and developing new therapeutic strategies for related diseases.
Used in Diagnostics:
PTH-L-PROLINE can be used as a biomarker for monitoring calcium levels and bone metabolism in various conditions, aiding in the diagnosis and management of diseases related to bone and mineral homeostasis.

Check Digit Verification of cas no

The CAS Registry Mumber 4333-21-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,3 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4333-21:
(6*4)+(5*3)+(4*3)+(3*3)+(2*2)+(1*1)=65
65 % 10 = 5
So 4333-21-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N2OS/c15-11-10-7-4-8-13(10)12(16)14(11)9-5-2-1-3-6-9/h1-3,5-6,10H,4,7-8H2

4333-21-5 Well-known Company Product Price

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  • TCI America

  • (P0729)  Phenylthiohydantoin-proline  >98.0%(HPLC)(N)

  • 4333-21-5

  • 100mg

  • 230.00CNY

  • Detail
  • TCI America

  • (P0729)  Phenylthiohydantoin-proline  >98.0%(HPLC)(N)

  • 4333-21-5

  • 1g

  • 990.00CNY

  • Detail

4333-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenylthiohydantoin-proline

1.2 Other means of identification

Product number -
Other names PTH-L-PROLINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4333-21-5 SDS

4333-21-5Relevant academic research and scientific papers

Method for treating nerve injury caused as a result of surgery

-

, (2008/06/13)

The present invention relates generally to methods for treating or preventing nerve injury in a warm-blooded animal caused as a consequence of surgery by administering neurotrophic compounds described below. The invention relates more specifically to methods for treating or preventing nerve injury caused as a consequence of prostate surgery as well as erectile dysfunction.

Hydantoin derivative compounds, pharmace utical compositions, and methods of using same

-

, (2008/06/13)

The present invention relates generally to novel hydantoin derivative compounds, pharmaceutical compositions containing such compounds, and methods for their use in preventing and/or treating neurological disorders, including physically damaged nerves and neurodegenerative diseases; for treating alopecia and promoting hair growth; for treating vision disorders and/or improving vision; for treating memory impairment and/or enhancing memory performance; and for treating sensorineural hearing loss by administering such compounds.

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