433332-82-2Relevant academic research and scientific papers
Synthesis of monocyclic hydroperoxy- and hydroxy-substituted sulfin- and sulfonamides by oxidation of 4,5-dimethylisothiazolium salts
Taubert, Kathleen,Sieler, Joachim,Hennig, Lothar,Findeisen, Matthias,Schulze, Baerbel
, p. 183 - 195 (2007/10/03)
The isothiazolium salts 10, easily accessible by cyclocondensation of the thiocyanates 8 with the anilines 9, yielded with H2O2 as the oxidant the first stable hydroperoxides of the 2-aryl-2,3-dihydroisothiazole 1-oxides rac-cis-13, the 1,1-dioxides 15, and their reduced 3-hydroxy derivatives rac-cis-14 and 16, respectively. The oxidation of 10 to new isothiazol-3(2H)-one 1,1-dioxides (17) is also described. For the first time, an aryl-bridged bis[isothiazolium salt] 11 was synthesized and oxidized.
