433684-68-5

Basic information

• Product Name: (E)-1-(naphthalen-2-yl)but-2-en-1-ol
• Synonyms: (E)-1-(naphthalen-2-yl)but-2-en-1-ol
• CAS NO: 433684-68-5
• Molecular Weight: 198.265
• Mol File: 433684-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(naphthalen-2-yl)but-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(naphthalen-2-yl)but-2-en-1-ol(433684-68-5)
• EPA Substance Registry System: (E)-1-(naphthalen-2-yl)but-2-en-1-ol(433684-68-5)

Safety Data

• Hazardous Substances Data: 433684-68-5(Hazardous Substances Data)

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 21473-01-8 2-naphthalenylmagnesium bromide 

Relevant articles and documents

Isothiourea-Catalysed Acylative Kinetic Resolution of Aryl–Alkenyl (sp2vs. sp2) Substituted Secondary Alcohols

The non-enzymatic acylative kinetic resolution of challenging aryl–alkenyl (sp2vs. sp2) substituted secondary alcohols is described, with effective enantiodiscrimination achieved using the isothiourea organocatalyst HyperBTM (1 mol %) and isobutyric anhydride. The kinetic resolution of a wide range of aryl–alkenyl substituted alcohols has been evaluated, with either electron-rich or naphthyl aryl substituents in combination with an unsubstituted vinyl substituent providing the highest selectivity (S=2–1980). The use of this protocol for the gram-scale (2.5 g) kinetic resolution of a model aryl–vinyl (sp2vs. sp2) substituted secondary alcohol is demonstrated, giving access to >1 g of each of the product enantiomers both in 99:1 e.r.