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Guanidine, (2-mercaptoethyl)-, monohydrobromide, also known as GMBS (Guanidinium 2-mercaptoethanesulfonate), is a chemical compound widely utilized in the field of biological research, specifically in molecular biology. Guanidine, (2-mercaptoethyl)-, monohydrobromide functions as a protein crosslinker, featuring a thiol reactive group that can interact with sulfhydryl groups on proteins, thereby creating stable bonds. It is also used as a precursor for the synthesis of other chemical substances. Due to its potential to cause skin, eye, and respiratory irritation, as well as other health hazards, proper handling precautions are essential.

4337-69-3

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Basic information
1. Product Name: Guanidine, (2-mercaptoethyl)-, monohydrobromide
2. Synonyms: 2-Mercaptoethylguanidine-hydrobromide; 2-(2-sulfanylethyl)guanidine; Ethanethiol, 2-guanidino-; 2-Mercaptoethylguanidine hydrobromide; 2-Mercaptoethylguanidine; N-Guanidylcysteamin [German]; 2-Guanidinoethanethiol; (N-(2-sulfanylethyl)carbamimidoyl)azanium bromide
3. CAS NO:4337-69-3
4. Molecular Formula: C₃H₁₀BrN₃S
5. Molecular Weight: 200.1006
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 4337-69-3.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 264.9 °C at 760 mmHg
3. Flash Point: 114 °C
4. Appearance: N/A
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Guanidine, (2-mercaptoethyl)-, monohydrobromide(CAS DataBase Reference)
10. NIST Chemistry Reference: Guanidine, (2-mercaptoethyl)-, monohydrobromide(4337-69-3)
11. EPA Substance Registry System: Guanidine, (2-mercaptoethyl)-, monohydrobromide(4337-69-3)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 4337-69-3(Hazardous Substances Data)

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4337-69-3 Usage

Uses

Used in Biological Research:
Guanidine, (2-mercaptoethyl)-, monohydrobromide is used as a protein crosslinker for [creating stable bonds between proteins and other particles] in molecular biology. Its thiol reactive group allows for the formation of covalent bonds with sulfhydryl groups on proteins, facilitating various experimental techniques and applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Guanidine, (2-mercaptoethyl)-, monohydrobromide is used as a precursor for [the synthesis of other chemical substances] that may have therapeutic applications. Its role in creating stable bonds can be leveraged to develop novel drug delivery systems, potentially improving the efficacy and bioavailability of certain medications.
Used in Diagnostic Applications:
Guanidine, (2-mercaptoethyl)-, monohydrobromide is used as a reagent for [enhancing the detection and analysis of proteins] in diagnostic applications. Its ability to form stable bonds with proteins can aid in the development of more accurate and sensitive diagnostic tools, contributing to the advancement of medical diagnostics.

Check Digit Verification of cas no

The CAS Registry Mumber 4337-69-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,3 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4337-69:
(6*4)+(5*3)+(4*3)+(3*7)+(2*6)+(1*9)=93
93 % 10 = 3
So 4337-69-3 is a valid CAS Registry Number.