4337-69-3

Basic information

• Product Name: Guanidine, (2-mercaptoethyl)-, monohydrobromide
• Synonyms: 2-Mercaptoethylguanidine-hydrobromide; 2-(2-sulfanylethyl)guanidine; Ethanethiol, 2-guanidino-; 2-Mercaptoethylguanidine hydrobromide; 2-Mercaptoethylguanidine; N-Guanidylcysteamin [German]; 2-Guanidinoethanethiol; (N-(2-sulfanylethyl)carbamimidoyl)azanium bromide
• CAS NO: 4337-69-3
• Molecular Formula: C₃H₁₀BrN₃S
• Molecular Weight: 200.1006
• Mol File: 4337-69-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 264.9 °C at 760 mmHg
• Flash Point: 114 °C
• CAS DataBase Reference: Guanidine, (2-mercaptoethyl)-, monohydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: Guanidine, (2-mercaptoethyl)-, monohydrobromide(4337-69-3)
• EPA Substance Registry System: Guanidine, (2-mercaptoethyl)-, monohydrobromide(4337-69-3)

Safety Data

• Hazardous Substances Data: 4337-69-3(Hazardous Substances Data)

Usage

General Description

Guanidine, (2-mercaptoethyl)-, monohydrobromide is a chemical compound often used within the realm of biological research, particularly in molecular biology. Also known as GMBS (Guanidinium 2-mercaptoethanesulfonate), this compound acts as a protein crosslinker with a thiol reactive group on one end that can react with sulfhydryl groups on proteins. It is often used to create stable bonds between proteins and other particles, and may also serve as a precursor for other chemical substances. Like other chemical compounds, proper caution is needed when handling, with the potential to cause skin, eye, and respiratory irritation, as well as posing other health hazards.

Synthetic route

(2-mercapto-ethyl)-guanidine; hydrobromide (4337-69-3) + Rifamycin S (13553-79-2, 62623-68-1, 76188-88-0, 81203-58-9, 101978-28-3) → 3-(2-Guanidino-aethylmercapto)-rifamycin SV (15299-46-4)

Conditions	Yield
With triethylamine In ethanol at 20℃; for 22h;

Downstream Products

• 15299-46-4 3-(2-Guanidino-aethylmercapto)-rifamycin SV