4338-50-5 Usage
Classification
Synthetic carbonic anhydrase inhibitor
Medical Uses
Diuretic: Increases excretion of sodium, potassium, and bicarbonate in the kidneys.
Treatment of Glaucoma: Decreases production of aqueous humor, reducing intraocular pressure.
Treatment of Epilepsy: Adjunctive treatment for certain types of seizures.
Treatment of Altitude Sickness: Prophylactic treatment to prevent or alleviate symptoms.
Treatment of Neurological Disorders: Used in some neurological conditions.
Physical Properties
Appearance: White, odorless crystalline powder.
Solubility: Sparingly soluble in water, slightly soluble in alcohol.
Mechanism of Action
Carbonic Anhydrase Inhibition: Inhibits carbonic anhydrase enzyme, reducing bicarbonate production.
Effects
Ocular Effects: Reduces intraocular pressure by decreasing aqueous humor production.
Renal Effects: Increases excretion of sodium, potassium, and bicarbonate.
Metabolic Effects: Leads to metabolic acidosis due to decreased bicarbonate reabsorption.
Respiratory Effects: Increases respiratory rate to compensate for acidosis.
Prophylactic Action Against Altitude Sickness
Bicarbonate Reduction: Decreases bicarbonate reabsorption in kidneys, helping to normalize pH.
Symptom Alleviation: Reduces symptoms associated with altitude sickness.
Administration
Typically administered orally, in tablet form.
Contraindications
Not suitable for individuals with certain renal or hepatic impairments.
Side Effects
May include electrolyte imbalances, metabolic acidosis, gastrointestinal disturbances.
Dosage
Administered in various doses depending on the condition being treated.
Monitoring
Periodic monitoring of electrolyte levels and renal function may be necessary during treatment.
Interactions
Can interact with other medications, particularly those affecting electrolyte balance.
Special Considerations
Adjustments may be needed in patients with renal or hepatic dysfunction.
Check Digit Verification of cas no
The CAS Registry Mumber 4338-50-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,3 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4338-50:
(6*4)+(5*3)+(4*3)+(3*8)+(2*5)+(1*0)=85
85 % 10 = 5
So 4338-50-5 is a valid CAS Registry Number.
