433939-92-5Relevant academic research and scientific papers
Heterocyclyl substituted 1-alkoxy acetic acid amides
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Page/Page column 19, (2010/02/12)
The invention is concerned with novel heterocyclyl substituted 1-alkoxy acetic acid derivatives of formula (I) wherein R1 to R6 and A are as defined in the description and in the claims, as well as physiologically acceptable salts th
Mandelic acid derivatives and their use as throbin inhibitors
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Page/Page column 47, (2008/06/13)
There is provided a compound of formula I wherein Ra, R1, R2, Y and R3 have meanings given in the description and pharmaceutically acceptable derivatives (including prodrugs) thereof, which compounds and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
