433955-11-4Relevant academic research and scientific papers
A new and efficient synthesis of substituted 2-hydroxymethyl-2-methyl-2H-chromenes
Goujon,Zammattio,Pagnoncelli,Boursereau,Kirschleger
, p. 322 - 324 (2007/10/03)
A new and efficient three step procedure for the synthesis of functionalized 2H-chromenes 1 is described, starting from commercially available salicylaldehydes 2 and 2-methylpropenyl-magnesium chloride 3, which involves catalytic acid-mediated intramolecular cyclization of phenolic epoxide 5 as the key step.
