433976-93-3Relevant academic research and scientific papers
The influence of stereochemistry on anion binding and transport
Karagiannidis, Louise E.,Hiscock, Jennifer R.,Gale, Philip A.
, p. 626 - 630 (2013)
Bis(thio)urea receptors (1-4) based on 1,2-bisaminocyclohexane are shown to function as transmembrane anion antiporters. The results show that cis-receptors have a greater propensity for anion transport than analogous trans-receptors. Stability constants using 1H NMR techniques highlight the significance of stereoisomerism on anion binding in solution, as cis-receptors bind anions more strongly than trans-receptors.
