4349-08-0

Basic information

• Product Name: 4(1H)-Pyrimidinone, 5-chloro- (9CI)
• Synonyms: 4(1H)-Pyrimidinone, 5-chloro- (9CI);4(1H)-Pyrimidinone,5-chloro-
• CAS NO: 4349-08-0
• Molecular Formula: C4H3ClN2O
• Molecular Weight: 130.53242
• Product Categories: PYRIMIDINE
• Mol File: 4349-08-0.mol

Chemical Properties

• Melting Point: 177-179 °C(Solv: water (7732-18-5))
• Boiling Point: 233.7 °C at 760 mmHg
• Flash Point: 95.2 °C
• Appearance: /
• Density: 1.55 g/cm³
• Vapor Pressure: 0.0361mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.25±0.40(Predicted)
• CAS DataBase Reference: 4(1H)-Pyrimidinone, 5-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 5-chloro- (9CI)(4349-08-0)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 5-chloro- (9CI)(4349-08-0)

Safety Data

• Hazardous Substances Data: 4349-08-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4(1H)-Pyrimidinone, 5-chloro(9CI) is used as a key intermediate in the synthesis of antiviral and anticancer drugs. Its unique structure allows for the development of novel therapeutic agents that target specific viral and cancer-related pathways, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 4(1H)-Pyrimidinone, 5-chloro(9CI) serves as a crucial component in the production of various pesticides and herbicides. Its incorporation into these compounds enhances their effectiveness in controlling pests and weeds, thereby improving crop yields and ensuring food security.
Used in Materials Science:
4(1H)-Pyrimidinone, 5-chloro(9CI) is utilized in the development of innovative materials and compounds for a variety of industrial applications. Its unique chemical properties enable the creation of new materials with improved performance characteristics, such as enhanced stability, reactivity, or selectivity, which can be applied in various industries, including electronics, coatings, and polymers.
Overall, 4(1H)-Pyrimidinone, 5-chloro(9CI) is a valuable chemical compound with diverse applications across different industries, showcasing its importance in the development of new products and technologies.

InChI:InChI=1/C4H3ClN2O/c5-3-1-6-2-7-4(3)8/h1-2H,(H,6,7,8)

Upstream product

• 51953-18-5 pyrimidine-4(3H)-one 

Downstream Products

• 6554-61-6 4,5-dichloropyrimidine 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS

Compounds of formula (I) are useful in the treatment of vanilloid-receptor-meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.