DCJTB, also known as 2,7-dichlorodihydrofluorescein diacetate, is a chemical compound widely utilized in scientific research for the detection of reactive oxygen species (ROS) in cells. It is transformed into a fluorescent dye by intracellular esterases, which specifically binds to ROS, enabling researchers to visualize and quantify ROS levels. This capability makes DCJTB an essential tool for investigating the role of ROS in various biological processes, such as oxidative stress and inflammation, and holds potential for applications in drug development and clinical diagnostics.
434938-12-2
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Basic information
- Product Name: DCJTB
- Synonyms: Propanedinitrile, 2-[2-(1,1-dimethylethyl)-6-[2-(2,3,6,7-tetrahydro-1,1,6,6-tetramethyl-1H,5H-benzo[ij]quinolizin-9-yl)ethenyl]-4H-pyran-4-ylidene]-
- CAS NO:434938-12-2
- Molecular Formula: C30H41NO
- Molecular Weight: 431.65264
- EINECS: -0
- Product Categories: N/A
- Mol File: 434938-12-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: DCJTB(CAS DataBase Reference)
- NIST Chemistry Reference: DCJTB(434938-12-2)
- EPA Substance Registry System: DCJTB(434938-12-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 434938-12-2(Hazardous Substances Data)
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434938-12-2 Usage
Uses
Used in Scientific Research:DCJTB is used as a detection agent for reactive oxygen species (ROS) in cells, allowing researchers to visualize and measure ROS levels. This is crucial for studying the involvement of ROS in biological processes and their role in health and disease.
Used in Drug Development:
DCJTB is used as a research tool to evaluate the effects of potential drugs on ROS levels in cells. This helps in understanding the drug's impact on oxidative stress and inflammation, which are often associated with various diseases.
Used in Clinical Diagnostics:
DCJTB is used as a diagnostic agent to assess ROS levels in clinical samples, providing insights into the oxidative stress status of patients and aiding in the diagnosis and monitoring of diseases related to ROS imbalance.
Used in Oxidative Stress and Inflammation Studies:
DCJTB is used as a research tool to investigate the role of ROS in oxidative stress and inflammation, helping to uncover the underlying mechanisms and potential therapeutic targets for related diseases.
Used in Cellular Imaging:
DCJTB is used as a fluorescent probe for cellular imaging, enabling researchers to visualize the distribution and dynamics of ROS within cells, providing valuable information for understanding cellular processes and responses to various stimuli.
Check Digit Verification of cas no
The CAS Registry Mumber 434938-12-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,4,9,3 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.Calculate Digit Verification of CAS Registry Number 434938-12:
(8*4)+(7*3)+(6*4)+(5*9)+(4*3)+(3*8)+(2*1)+(1*2)=162
162 % 10 = 2
So 434938-12-2 is a valid CAS Registry Number.
434938-12-2Upstream product
434938-12-2Downstream Products
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DCJTB
