5β-pregnan-3α-ol, also known as pregnanolone, is a naturally occurring neurosteroid derived from the steroid hormone pregnenolone. It is a metabolite of progesterone and plays a significant role in the central nervous system, acting as a positive allosteric modulator of the GABA-A receptor, which enhances the inhibitory effects of GABA, the primary inhibitory neurotransmitter in the brain. This action can lead to sedative, anxiolytic, and anticonvulsant effects. Pregnanolone is synthesized in the brain and has been implicated in various physiological processes, including stress response, mood regulation, and cognitive function. It is also found in small amounts in the blood and has been studied for its potential therapeutic applications in conditions such as anxiety, depression, and neurological disorders.
The CAS Registry Mumber 4352-07-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,5 and 2 respectively; the second part has 2 digits, 0 and 7 respectively. Calculate Digit Verification of CAS Registry Number 4352-07: (6*4)+(5*3)+(4*5)+(3*2)+(2*0)+(1*7)=72 72 % 10 = 2 So 4352-07-2 is a valid CAS Registry Number.