4353-00-8Relevant academic research and scientific papers
Cross-metathesis reaction of functionalized and substituted olefins using group 8 transition metal carbene complexes as metathesis catalysts
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Page/Page column 36; 45, (2016/08/29)
The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.
Highly efficient acetalization of carbonyl compounds catalyzed by anilin-aldehyde resin salts
Tanemura, Kiyoshi,Suzuki, Tsuneo
supporting information, p. 797 - 799 (2015/06/22)
A mild procedures for the syntheses of ethylene acetals and dimethyl acetals from the corresponding aldehydes and ketones catalyzed by 1mol% of anilinealdehyde resin salts are described. This method is also useful for the synthesis of dimethyl acetals of diaryl ketones.
Solvent free protection of carbonyl group under microwave irradiation
Perio, Bertrand,Dozias, Marie-Joelle,Jacquault, Patrick,Hamelin, Jack
, p. 7867 - 7870 (2007/10/03)
Protection of aldehydes and ketones as acetals or dioxolanes catalysed by PTSA or KSF clay was readily achieved from orthoformates, 1,2-ethanediol or 2,2-dimethyl-1,3-dioxolane without solvent under microwave irradiation.
Regioselective Alkylation of 1,3-Dioxolan-2-ylium Cation Derived from α,β-Unsaturated Aldehyde Ethylene Acetal with Lithium Organo Compounds
Mukaiyama, Teruaki,Hayashi, Yujiro,Hashimoto, Yukihiko
, p. 1627 - 1630 (2007/10/02)
1,3-Dioxolan-2-ylium cations derived from α,β-unsaturated aldehyde ethylene acetals regioselectively react with lithium organocuprate and lithium organoaluminate to give the corresponding esters and ketals, respectively.
