(3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID, commonly known as almitrine, is a pharmaceutical compound with potent respiratory stimulant properties. It is characterized by its ability to enhance oxygen uptake and utilization while facilitating airway dilation, thereby improving respiratory function. Almitrine operates through the stimulation of peripheral chemoreceptors, increasing the sensitivity of central respiratory centers to carbon dioxide, and reducing the conductivity of the vagus nerve. This unique mechanism of action positions almitrine as a valuable therapeutic agent in the treatment of respiratory disorders.
435342-05-5
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Basic information
- Product Name: (3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID
- Synonyms: (3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID;(3-Allyl-2-imino-2,3-dihydro-benzoimidazol-1-yl)-
- CAS NO:435342-05-5
- Molecular Formula: C12H13N3O2
- Molecular Weight: 231.25
- EINECS: N/A
- Product Categories: N/A
- Mol File: 435342-05-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 396.4 °C at 760 mmHg
- Flash Point: 193.5 °C
- Appearance: /
- Density: 1.27 g/cm3
- Vapor Pressure: 5.39E-07mmHg at 25°C
- Refractive Index: 1.626
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID(CAS DataBase Reference)
- NIST Chemistry Reference: (3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID(435342-05-5)
- EPA Substance Registry System: (3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID(435342-05-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 435342-05-5(Hazardous Substances Data)
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435342-05-5 Usage
Uses
Used in Pharmaceutical Industry:Almitrine is utilized as a respiratory stimulant for the treatment of chronic obstructive pulmonary disease (COPD) and other respiratory illnesses. Its application is based on its capacity to improve oxygenation and respiratory efficiency, providing relief from symptoms associated with lung diseases.
Used in Combination Therapy:
In the healthcare sector, almitrine is often administered alongside other medications to synergistically enhance respiratory function and alleviate symptoms of lung disorders. The combined use of almitrine with other therapeutic agents aims to optimize treatment outcomes and improve the overall management of respiratory conditions.
Used in Respiratory Research:
Almitrine's unique mode of action also makes it a subject of interest in respiratory research. It is studied for its potential to advance understanding of respiratory physiology and to develop new therapeutic strategies for treating various respiratory ailments.
Check Digit Verification of cas no
The CAS Registry Mumber 435342-05-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,5,3,4 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.Calculate Digit Verification of CAS Registry Number 435342-05:
(8*4)+(7*3)+(6*5)+(5*3)+(4*4)+(3*2)+(2*0)+(1*5)=125
125 % 10 = 5
So 435342-05-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O2/c1-2-7-14-9-5-3-4-6-10(9)15(12(14)13)8-11(16)17/h2-6,13H,1,7-8H2,(H,16,17)
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435342-05-5Downstream Products
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(3-ALLYL-2-IMINO-2,3-DIHYDRO-BENZOIMIDAZOL-1-YL)-ACETIC ACID
