4357-31-7

Basic information

• Product Name: 4-(4-Ethoxyphenyl)pyridine
• Synonyms: 4-(4-Ethoxyphenyl)pyridine
• CAS NO: 4357-31-7
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.24842
• Mol File: 4357-31-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(4-Ethoxyphenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Ethoxyphenyl)pyridine(4357-31-7)
• EPA Substance Registry System: 4-(4-Ethoxyphenyl)pyridine(4357-31-7)

Safety Data

• Hazardous Substances Data: 4357-31-7(Hazardous Substances Data)

Usage

General Description

4-(4-Ethoxyphenyl)pyridine is a chemical compound with the molecular formula C13H13NO that belongs to the pyridine family. It is a yellow solid with a melting point of 81-83 °C and a boiling point of 129-130 °C. This chemical is used in the synthesis of pharmaceutical intermediates and agrochemicals. It has been reported as an intermediate for the synthesis of active pharmaceutical ingredients, and it may also have potential applications in material science. Overall, 4-(4-Ethoxyphenyl)pyridine is a versatile chemical with diverse applications in the pharmaceutical and agrochemical industries.

Upstream product

• 110-86-1 pyridine 
• 38793-99-6 4-ethoxy-benzenediazonium; chloride 
• 3108-14-3 4-ethoxyphenylphenyldiazonium tetrafluoroborate 
• 1120-87-2 4-bromopyridin 
• 90591-48-3 tris-(4-ethoxy-phenyl)-bismuthine 
• 699-08-1 1-ethoxy-4-iodobenzene 
• 1692-15-5 4-pyridylboronic acid 

Downstream Products

• 760150-51-4 4-(4-ethoxy-phenyl)-piperidine 
• 1444778-48-6 (S)-1-cyano-cyclopropanecarboxylic acid (1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethyl)-amide 
• 1444779-19-4 (S)-N-(1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethyl)-N-methyl-acetamide 
• 1444778-76-0 (S)-2-acetylamino-oxazole-4-carboxylic acid (1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethyl)-amide 
• 1444779-16-1 (S)-(1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethyl)-carbamic acid methyl ester 
• 1444779-04-7 (S)-3-(1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethyl)-1-ethyl-1-methyl-urea 
• 1444780-57-7 (S)-1-{4-[4-(4-ethoxy-phenyl)-piperidin-1-yl]-phenyl}-ethylamine hydrochloride 

Relevant articles and documents

Triarylbismuthanes as threefold aryl-transfer reagents in regioselective cross-coupling reactions with bromopyridines and quinolines

Cross-coupling studies using bromopyridines and bromoquinolines with triarylbismuths as threefold coupling reagents in substoichiometric amounts under Pd-catalysed conditions are disclosed. The reactivity was high with both mono- and dibromopyridyl substrates, and mono- and bis-couplings were carried out regioselectively. A library of monoaryl and diaryl pyridines was formed in high yields. A one-pot strategy provided a simple and straightforward synthesis of both symmetrical and unsymmetrical diarylpyridines. Arylations of 2-bromo- and 3-bromoquinolines were achieved with triarylbismuth reagents. This study demonstrates that triarylbismuths may be used as threefold arylating reagents for the synthesis of aryl pyridines and quinolines through couplings with bromopyridines and bromoquinolines under Pd-catalysed conditions. Copyright

New piperidine derivatives, pharmaceutical compositions and uses thereof

The invention relates to new piperidine derivatives of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

Piperidine Derivatives

Piperidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.