4359-54-0

Usage

Uses

Used in Flavoring Agents:
2-(2-furyl)-4-methyl-1,3-dioxolane is used as a flavoring agent in the food industry for its ability to impart sweet and fruity flavors, enhancing the taste profiles of various food products.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-(2-furyl)-4-methyl-1,3-dioxolane serves as an important intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, 2-(2-furyl)-4-methyl-1,3-dioxolane is utilized in the synthesis of different agrochemicals, playing a role in the creation of products for agricultural applications.
Safety Precautions:
It is crucial to handle 2-(2-furyl)-4-methyl-1,3-dioxolane with care due to its potential harmful effects if ingested, inhaled, or comes into contact with skin or eyes, emphasizing the need for proper safety measures during its use.

InChI:InChI=1/C8H10O3/c1-6-5-10-8(11-6)7-3-2-4-9-7/h2-4,6,8H,5H2,1H3

Upstream product

• 98-01-1 furfural 
• 57-55-6 propylene glycol 

Relevant academic research and scientific papers

Zeolite-catalyzed acetalization reaction of furfural with alcohol under solvent-free conditions

Acetalization reactions present a viable method for producing valuable chemicals and protecting carbonyl functionalities in organic compounds. Herein, several commercial zeolites were used as solid acid catalysts in the acetalization of biomass-derived furfural with alcohols under solvent-free conditions. The effects of major reaction parameters such as catalyst concentration, reaction temperature, and reaction time were investigated. Among the tested catalysts, SAPO-34 with appropriate acid sites and textural structure exhibited the highest catalytic activity under optimized reaction conditions. Additionally, the catalyst showed excellent recyclability and no obvious deactivation was observed even after using it six times.

Synthesis of sulfonic acid-functionalized MIL-101 for acetalization of aldehydes with diols

A metal-organic framework (MOF) MIL-101 bearing sulfonic acid groups (SO3H-MIL-101), was prepared through one-pot hydrothermal synthesis strategy. This MOF was systemically characterized via XRD, N2 adsorption, acid-base titration, XPS, FT-IR techniques, and elemental analysis, and then used as a heterogeneous catalyst for liquid-phase acetalizations of various aldehydes with diols. The obtained SO3H-MIL-101 shows high catalytic activity in the acetalizations due to the high utilization efficiency of its functionalized acid sites. Additionally, this catalyst can be easily recovered and reused five times in succession without significant loss of catalytic activity.

Acetalization of carbonyl compounds catalyzed by acidic ionic liquid immobilized on silica gel

Imidazolium-silica heterogeneous catalyst (SG-[(CH2) 3SO3H-HIM]HSO4) was prepared by immobilization of acidic ionic liquid 1-(propyl-3-sulfonate) imidazolium hydrosulfate ([(CH2)3SO3H-HIM]HSO4) on silica-gel using tetraethoxysilane (TEOS) as silica source in this study. The properties of the samples were characterized by FT-IR, SEM and TG/DSC. The results suggested that [(CH2)3SO3H-HIM]HSO4 had been successfully immobilized on the surface of silica-gel and the immobilized ionic liquid catalyst SG-[(CH2)3SO 3H-HIM]HSO4 had good thermal stability. The original smooth surface of silica-gel was covered with [(CH2) 3SO3H-HIM]HSO4 and a rough surface of SG-[(CH2)3SO3H-HIM]HSO4 was formed, but the size of particles had no obvious change. Moreover, SG-[(CH 2)3SO3H-HIM]HSO4 exhibited high catalytic activity for a series of acetalization and could be recovered easily. After reused for 10 times in the synthesis of benzaldehyde ethanediol acetal, the catalyst could still give satisfactory catalytic activity.

New catalytic methods for the preparation of acetals from alcohols and aldehydes

The acetalization of aldehydes has been studied with ethyleneglycol, 3-chloro-1,2-propanediol, 1,2-propanediol, and 1,2,3-propanetriol using resin-D72 catalyst in high yields under reflux and water separator conditions. The reaction is simple, efficient, and chemoselective and does not involve any other additive. Copyright Taylor & Francis Group, LLC.

1H NMR spectra, configuration, and conformations of 2-mono- and 2,4-disubstituted 1,3-dioxolanes

The stereochemistry of 2-furyl-substituted 1,3-dioxolanes was studied. The ethane fragment of 2-monosubstituted dioxolanes displays the spectrum that is typical for an AA'BB' spin system, while the spectra of the 2,4-disubstituted compounds are typical for an ABC system. The contribution of the various conformational forms to the pseudorotation cycle of the dioxolanes is discussed on the basis of an analysis of the spectra by means of an iteration program.