436091-35-9 Usage
Uses
Used in Pharmaceutical Industry:
MPTA is used as an intermediate in the synthesis of various compounds for the pharmaceutical industry. Its versatile nature allows for the creation of a wide range of drugs with different therapeutic applications.
Used in Anti-inflammatory Applications:
MPTA is used as an anti-inflammatory agent due to its potential therapeutic properties. It may help in reducing inflammation and providing relief from conditions associated with inflammation.
Used in Analgesic Applications:
MPTA is also used as an analgesic, which means it has the ability to relieve pain. Its potential therapeutic properties make it a valuable compound in the development of pain-relieving medications.
Used in Drug Development:
MPTA serves as a building block for the development of new drugs. Its various biological activities and potential therapeutic applications make it an essential component in the creation of innovative pharmaceuticals.
Used in Research and Development:
MPTA is used in pharmaceutical research and development to explore its potential in treating various conditions and to develop new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 436091-35-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,6,0,9 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 436091-35:
(8*4)+(7*3)+(6*6)+(5*0)+(4*9)+(3*1)+(2*3)+(1*5)=139
139 % 10 = 9
So 436091-35-9 is a valid CAS Registry Number.
436091-35-9Relevant academic research and scientific papers
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators
Sharma, Swagat,Kozek, Krystian A.,Abney, Kristopher K.,Kumar, Sushil,Gautam, Nagsen,Alnouti, Yazen,David Weaver,Hopkins, Corey R.
, p. 791 - 796 (2019/02/06)
The present study describes the discovery and characterization of a series of 5-aryl-2H-tetrazol-3-ylacetamides as G protein-gated inwardly-rectifying potassium (GIRK) channels activators. Working from an initial hit discovered during a high-throughput screening campaign, we identified a tetrazole scaffold that shifts away from the previously reported urea-based scaffolds while remaining effective GIRK1/2 channel activators. In addition, we evaluated the compounds in Tier 1 DMPK assays and have identified a (3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene-1,1-dioxide head group that imparts interesting and unexpected microsomal stability compared to previously-reported pyrazole head groups.
