436148-62-8

Upstream product

• 121964-07-6 2,3-di-O-benzyl-4,5-O-isopropylidene-D-arabinitol 
• 98-59-9 p-toluenesulfonyl chloride 
• 106929-09-3 (2S,3R,4R)-2,3-dibenzyloxy-4,5-isopropylidenedioxypentanal 
• 111476-62-1 3,4-di-O-benzyl-1,2:5,6-di-O-isopropylidene-D-mannitol 
• 121964-05-4 3,4-di-O-benzyloxy-5,6-O-isopropylidene-D-mannitol 

Downstream Products

• 436148-70-8 (4R,5S)-4,5-Bis-benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-2-(3,4,5-trimethoxy-phenyl)-pentanenitrile 
• 436148-69-5 (4R,5S)-2-Benzo[1,3]dioxol-5-yl-4,5-bis-benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-pentanenitrile 
• 436148-65-1 (4R,5S)-4,5-Bis-benzyloxy-2-(4-chloro-phenyl)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-pentanenitrile 
• 436148-68-4 (4R,5S)-4,5-Bis-benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-(4-fluoro-phenyl)-2-morpholin-4-yl-pentanenitrile 
• 436148-66-2 (4R,5S)-4,5-Bis-benzyloxy-2-(3-chloro-phenyl)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-pentanenitrile 
• 436148-67-3 (4R,5S)-4,5-Bis-benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-2-p-tolyl-pentanenitrile 
• 436148-64-0 (4R,5S)-4,5-Bis-benzyloxy-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-morpholin-4-yl-2-phenyl-pentanenitrile 
• 436148-77-5 (3R,4S)-3,4-Bis-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(3,4,5-trimethoxy-phenyl)-butan-1-one 
• 436148-76-4 (3R,4S)-1-Benzo[1,3]dioxol-5-yl-3,4-bis-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butan-1-one 
• 436148-75-3 (3R,4S)-3,4-Bis-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-(4-fluoro-phenyl)-butan-1-one 
• 436148-74-2 (3R,4S)-3,4-Bis-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-p-tolyl-butan-1-one 
• 436148-72-0 (3R,4S)-3,4-Bis-benzyloxy-1-(4-chloro-phenyl)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butan-1-one 
• 436148-73-1 (3R,4S)-3,4-Bis-benzyloxy-1-(3-chloro-phenyl)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butan-1-one 
• 436148-71-9 (3R,4S)-3,4-Bis-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-phenyl-butan-1-one 

Relevant academic research and scientific papers

An efficient strategy for the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol: Total synthesis of (-)-muricatacin

A general approach towards the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol has been described. The approach has successfully been used for the total synthesis of (-)-muricatacin, an anti-tumor natural product.

Total synthesis of (-)- and (+)-lentiginosine

Total synthesis of (-)-lentiginosine was achieved from D-mannitol using highly stereoselective reactions. Similarly, (+)-lentiginosine was synthesized from L-tartaric acid.

Umpolung strategy for the synthesis of 2-deoxy-C-aryl glycosides: A serendipitous, efficient route for C-furanoside analogues

Matrix presented 2-Deoxy-C-aryl glycosides are potential synthetic targets as they form a very vital moiety of several biologically active natural products. This paper describes a synthetic route using an umpolung strategy, which has not been explored til