436799-34-7

Basic information

• Product Name: 3,5-DIBROMO-2-IODOPYRIDINE
• Synonyms: 3,5-DIBROMO-2-IODOPYRIDINE
• CAS NO: 436799-34-7
• Molecular Formula: C5H2Br2IN
• Molecular Weight: 362.78855
• Mol File: 436799-34-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 298.4°C at 760 mmHg
• Flash Point: 134.3°C
• Appearance: /
• Density: 2.646g/cm³
• Vapor Pressure: 0.00226mmHg at 25°C
• Refractive Index: 1.693
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,5-DIBROMO-2-IODOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIBROMO-2-IODOPYRIDINE(436799-34-7)
• EPA Substance Registry System: 3,5-DIBROMO-2-IODOPYRIDINE(436799-34-7)

Safety Data

• Hazardous Substances Data: 436799-34-7(Hazardous Substances Data)

Usage

General Description

3,5-Dibromo-2-iodopyridine is a chemical compound with the molecular formula C5H3Br2IN. It is a halogenated pyridine derivative, which is commonly used as a building block in organic synthesis and pharmaceutical drug development. 3,5-DIBROMO-2-IODOPYRIDINE is a highly reactive and versatile reagent, with a wide range of applications in the synthesis of various organic compounds. Its unique combination of bromine and iodine atoms makes 3,5-dibromo-2-iodopyridine a valuable tool in the development of new drugs and agrochemicals. It is also used as an intermediate in the synthesis of complex natural products and biologically active compounds. However, it is important to handle this compound with caution, as it may be harmful if ingested or inhaled, and can cause skin and eye irritation upon contact.

InChI:InChI=1/C5H2Br2IN/c6-3-1-4(7)5(8)9-2-3/h1-2H

Upstream product

• 625-92-3 3,5-dibromopyridine 
• 75806-85-8 2,3,5-tribromopyridine 
• 35486-42-1 2-amino-3,5-dibromopyridine 

Downstream Products

• 436799-35-8 3,5-dibromo-2-(trifluoromethyl)pyridine 

Relevant articles and documents

Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships

A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.

Mixed Mg/Li amides of the type R2NMgCl·LiCl as highly efficient bases for the regioselective generation of functionalized aryl and heteroaryl magnesium compounds

(Chemical Equation Presented) Two are better than one: Mixed lithium-magnesium complexes of the type R2NMgCl·LiCl are kinetically highly active bases that convert a range of polyfunctional aromatic and heteroaromatic substrates into the corresponding magnesiated derivatives with high regioselectivity.