436799-34-7

Usage

Uses

Used in Organic Synthesis:
3,5-DIBROMO-2-IODOPYRIDINE is used as a building block for the synthesis of various organic compounds, leveraging its high reactivity and unique halogenated structure to facilitate the creation of a broad spectrum of chemical entities.
Used in Pharmaceutical Drug Development:
In the pharmaceutical industry, 3,5-DIBROMO-2-IODOPYRIDINE is utilized as a key intermediate in the development of new drugs, contributing to the design and synthesis of novel therapeutic agents that target a range of medical conditions.
Used in Agrochemical Development:
3,5-DIBROMO-2-IODOPYRIDINE is employed as a versatile reagent in the agrochemical sector, aiding in the synthesis of innovative compounds designed to protect crops and enhance agricultural productivity.
Used in the Synthesis of Complex Natural Products:
3,5-DIBROMO-2-IODOPYRIDINE is used as an intermediate in the synthesis of complex natural products, enabling the production of intricate molecular structures with potential applications in various fields, including medicine and biotechnology.
Used in the Synthesis of Biologically Active Compounds:
3,5-DIBROMO-2-IODOPYRIDINE is utilized in the synthesis of biologically active compounds, playing a crucial role in the development of substances that can interact with biological systems, potentially leading to new treatments and therapies.

InChI:InChI=1/C5H2Br2IN/c6-3-1-4(7)5(8)9-2-3/h1-2H

Upstream product

• 35486-42-1 2-amino-3,5-dibromopyridine 
• 75806-85-8 2,3,5-tribromopyridine 
• 625-92-3 3,5-dibromopyridine 

Downstream Products

• 436799-35-8 3,5-dibromo-2-(trifluoromethyl)pyridine 

Relevant academic research and scientific papers

Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships

A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.

5, 7-DIHYDRO- 6H-PYRIMIDO [ 5, 4-D] [ 1 ] BENZAZEPIN-6-THIONES AS PLK INHIBITORS

This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

Mixed Mg/Li amides of the type R2NMgCl·LiCl as highly efficient bases for the regioselective generation of functionalized aryl and heteroaryl magnesium compounds

(Chemical Equation Presented) Two are better than one: Mixed lithium-magnesium complexes of the type R2NMgCl·LiCl are kinetically highly active bases that convert a range of polyfunctional aromatic and heteroaromatic substrates into the corresponding magnesiated derivatives with high regioselectivity.

Trifluoromethyl-substituted pyridines through displacement of iodine by in situ generated (trifluoromethyl)copper

A literature method reported for iodobenzene and congeners was successfully extended to the pyridine series. 2-Iodopyridines can be converted into 2-(trifluoromethyl)pyridines almost quantitatively. In contrast, yields are moderate at best if 3- and 4-iodopyridines or 2-bromopyridines are used as the starting materials. WILEY-VCH Verlag GmbH 2002.