436851-94-4

Usage

Uses

Used in Pharmaceutical and Chemical Research:
4-Pyrimidinemethanol, 6-amino(9CI) is used as a building block for the synthesis of various organic compounds and pharmaceuticals. Its versatile chemical structure allows for the development of new molecules with potential therapeutic applications.
Used in Drug Development:
Due to its potential biological activity, 4-Pyrimidinemethanol, 6-amino(9CI) has been studied for its role in drug development. Its unique chemical structure may contribute to the creation of new drugs and pharmaceuticals with improved efficacy and selectivity.
Used in the Development of New Drugs and Pharmaceuticals:
4-Pyrimidinemethanol, 6-amino(9CI) may have applications in the development of new drugs and pharmaceuticals. Its unique chemical structure and potential biological properties make it a valuable component in the design and synthesis of novel therapeutic agents.

Upstream product

• 77817-12-0 methyl 6-aminopyrimidine-4-carboxylate 

Downstream Products

• 1378037-96-7 {6-[2-(2,6-dichlorophenyl)-7-methoxy-2H-pyrazolo[4,3-c]pyridin-4-ylamino]-pyrimidin-4-yl}-methanol 
• 1378037-91-2 {6-[7-bromo-2-(2,6-dichloro-phenyl)-2H-pyrazolo[4,3-c]pyridin-4-ylamino]-pyrimidin-4-yl}-methanol 
• 1365990-80-2 3-chloro-2-[7-fluoro-4-(6-hydroxymethyl-pyrimidin-4-ylamino)-thiazolo[5,4-c]pyridin-2-yl]-benzonitrile 
• 1365990-77-7 3-chloro-2-[4-(6-hydroxymethylpyrimidin-4-ylamino)thiazolo[5,4-c]pyridin-2-yl]-benzonitrile 
• 1365992-29-5 2-((6-(2-(2,6-dichlorophenyl)thiazolo[5,4-c]pyridin-4-ylamino)pyrimidin-4-yl)methyl)isoindoline-1,3-dione 
• 1365989-56-5 N-(6-(aminomethyl)pyrimidin-4-yl)-2-(2,6-dichlorophenyl)thiazolo[5,4-c]pyridin-4-amine 

Relevant academic research and scientific papers

PYRAZOLO[4,3-C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula (I) wherein R1, R2, and Cy are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNα, IL12 and/or IL23 by administering the compound of the invention.

AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE

Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of 5 manufacturing a compound of Formula I

2, 7 -NAPHTHYRIDIN- 1 -ONE DERIVATIVES AS SYK KINASE INHIBITORS

Provided herein area novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated Syk kinase activity.

Tyrosine kinase inhibitors

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.