4377-63-3 Usage
Uses
Used in Pharmaceutical Industry:
6-Chlorochroman-2-one is used as a key intermediate in the synthesis of pharmaceuticals for its ability to modulate biological processes, contributing to the development of drugs for various therapeutic areas. It plays a crucial role in creating anticancer, anti-inflammatory, and antiviral agents, enhancing treatment options for a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 6-chlorochroman-2-one serves as a building block for the synthesis of compounds with pesticidal properties, helping to develop new agrochemicals that can protect crops from pests and diseases, thereby increasing agricultural productivity.
Used in Chemical Research:
6-Chlorochroman-2-one is utilized as a research tool in chemical studies, aiding scientists in understanding the structure-activity relationships of chromanone derivatives and exploring their potential applications in material science and other chemical domains.
Used in Biological Research:
As a research tool in biological studies, 6-chlorochroman-2-one helps researchers investigate its interactions with biological systems, providing insights into its potential as a modulator of biological processes and its implications for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 4377-63-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,7 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4377-63:
(6*4)+(5*3)+(4*7)+(3*7)+(2*6)+(1*3)=103
103 % 10 = 3
So 4377-63-3 is a valid CAS Registry Number.
4377-63-3Relevant academic research and scientific papers
Effet de groupe partant dans l'hydrolyse d'orthoesters cycliques: changement de conformere reactif dans l'hydrolyse des diethoxy-2,2 tetrahydropyrannes
Lamaty, Gerard,Lorente, Philippe,Moreau, Claude
, p. 2651 - 2656 (2007/10/02)
The rates of hydrolysis of 6-substituted 2,2-diethoxy-3,4-dihydrobenzo-1-pyrans (X=MeO, Me, H, Cl) were determined at two temperatures in water/dioxan 2:1 by volume.The observed change of sign of the Hammett ρ constants (ρH3O+=-0.8; ρAH=0.7) is characteristic of a phenolate leaving group, i.e. of the rate-determining cleavage of the endocyclic C-O bond in the systems here studied; these results cleary indicate a change in the nature of the reactive conformer in hydrolysis of 2,2-diethoxy tetrahydropyrans.
