437701-80-9Relevant academic research and scientific papers
OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH
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Page/Page column 36, (2011/02/18)
The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.
A novel synthetic approach towards pyrazole-4-carboxamides using N-(3-(dimethylamino)-2-formylacryloyl)formamide
Jachak, Madhukar N.,Ghagare, Maruti G.,Birari, Dilip R.,Rote, Ramhari V.,Kazi, Muddassar A.,Jachak, Sanjay M.,Toche, Raghunath B.
body text, p. 569 - 576 (2011/07/30)
A novel synthesis of pyrazole-4-carboxamides is reported. The reaction of N-(3-(dimethylamino)-2-formylacryloyl)formamide, an intermediate obtained by Vilsmeier-Haack formylation of acetonitrile, with hydrazine hydrate or monosubstituted hydrazines provid
OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH
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Page/Page column 77, (2010/04/03)
The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.
PURINE DERIVATIVES AS ADENOSINE AL RECEPTOR LIGANDS
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Page/Page column 43, (2009/05/28)
Compounds of formula (I), their preparation and use as pharmaceuticals (I), wherein X, Y, and Z are as defined herein.
DERIVATIVES OF IMIDAZO (1,2-A) PYRIDINE USEFUL AS MEDICAMENTS FOR TREATING GASTROINTESTINAL DISEASES
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Page/Page column 26, (2010/11/24)
This invention relates to newly identified imidazopyridine compounds of formula (I), to the use of such compounds in therapy and to their production.
