437717-47-0Relevant academic research and scientific papers
Synthesis of N-Heterocycles by Reductive Cyclization of Nitroalkenes Using Molybdenum Hexacarbonyl as Carbon Monoxide Surrogate
Su, Zhiyou,Liu, Bo,Liao, Hongze,Lin, Hou-Wen
, p. 4059 - 4066 (2020/06/21)
The development of a method that uses molybdenum hexacarbonyl [Mo(CO)6] as carbon monoxide (CO) surrogate for the palladium-catalyzed reductive cyclization of nitroalkenes into indoles or thienopyrroles is reported. Several types of nitroalkenes could be transformed into the desired products in excellent yields and in most cases with complete regioselectivities and higher yields than those previously reported with palladium/CO system.
Synthesis of Indoles by Palladium-Catalyzed Reductive Cyclization of β-Nitrostyrenes with Carbon Monoxide as the Reductant
Ferretti, Francesco,El-Atawy, Mohamed A.,Muto, Stefania,Hagar, Mohamed,Gallo, Emma,Ragaini, Fabio
supporting information, p. 5712 - 5715 (2015/09/15)
An efficient catalytic cyclization of β-nitrostyrenes to indoles was developed. The reaction was applied to the synthesis of 3-arylindoles and 2-alkylindoles. Given that in the latter case the starting β-nitrostyrenes can be easily obtained by a Henry reaction, the present method allows indoles to be obtained in a two-step sequence starting from cheap reactants.
NOVEL COMPOUNDS
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Page/Page column 44, (2011/02/18)
The present invention relates to new CGRP-antagonists of general formula I wherein U, V, X, Y, R1, R2, R3 and R4 are defined as in the description, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.
NOVEL PIPERIDINE-SUBSTITUTED INDOLES
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Page/Page column 8, (2008/06/13)
Disclosed are novel piperidine-substituted indoles-or heteroderivatives thereof of the formula 1: wherein R1, R5, R6, R7, A, B, D-E, Y, i, j, n and m are defined as below. The compounds of formula 1 are useful as agonists or antagonists of CCR-3. The pres
NOVEL PIPERIDINE-SUBSTITUTED INDOLES
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Page/Page column 18-19, (2008/06/13)
Accordingly, one object of the present invention are novel piperidine-substituted indoles- or heteroderivatives thereof of the formula (1) : wherein R1, R5, R6, R7, A, B, D-E, Y, i, j, n and m are defined as bel
NOVEL PIPERIDINE-SUBSTITUTED INDOLES- OR HETERODERIVATIVES THEREOF
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Page/Page column 23-24, (2008/06/13)
Accordingly, one object of the present invention are novel piperidine-substituted indoles- or heteroderivatives thereof of the formula(1) wherein R, R, R, A, B, D-E, X-W-V, Y, i, j, n and m are defined as below. Another object of the present inve
