437768-96-2Relevant academic research and scientific papers
1-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as glycine templates. Synthesis of fiscalin B
Hernandez, Fernando,Buenadicha, Felix L.,Avendao, Carmen,Soellhuber, Monica
, p. 3387 - 3398 (2007/10/03)
An excess of base allows the regio- and diastereoselective alkylation at C(4) of the glycine templates 1-methyl(isopropyl)-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones 9a and 9b without the need for N(2)-protecting groups. While the alkylation of
