438002-74-5

Upstream product

• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 131310-61-7 (2R,4aR,6S,7R,8aS)-6-Methyl-2-phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 

Downstream Products

• 438002-61-0 (E)-3-{(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-[(1R,3S)-1-benzyloxy-3-phenylsulfanyl-3-((2R,3S)-2-triisopropylsilanyloxymethyl-3,6-dihydro-2H-pyran-3-yloxy)-propyl]-2-methyl-tetrahydro-pyran-3-yloxy}-acrylic acid methyl ester 
• 438002-62-1 (E)-3-((2S,3R,5S,6R)-5-Benzyloxy-2-{(1R,3S)-1-benzyloxy-3-[(2R,3S)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-3-phenylselanyl-propyl}-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-yloxy)-acrylic acid methyl ester 
• 438002-43-8 (E)-3-{(2S,3R,5S,6R)-5-Benzyloxy-2-[(1R,3S)-1-benzyloxy-3-((2R,3S)-2-methoxymethoxymethyl-tetrahydro-pyran-3-yloxy)-3-phenylselanyl-propyl]-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-yloxy}-acrylic acid methyl ester 
• 438002-52-9 {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylselanyl-propoxy]-tetrahydro-pyran-2-yl}-methanol 
• 438002-60-9 {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylselanyl-propoxy]-3,6-dihydro-2H-pyran-2-yl}-methanol 
• 438002-58-5 {(2R,3S)-3-[(1S,3R)-3-Benzyloxy-3-((2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-methyl-3-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-1-phenylsulfanyl-propoxy]-3,6-dihydro-2H-pyran-2-yl}-methanol 
• 438002-92-7 (2R,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-[(1R,3S)-1-benzyloxy-3-phenylsulfanyl-3-((2R,3S)-2-triisopropylsilanyloxymethyl-3,6-dihydro-2H-pyran-3-yloxy)-propyl]-2-methyl-tetrahydro-pyran-3-ol 
• 438002-94-9 (2R,3R,5S,6R)-5-Benzyloxy-2-{(1R,3S)-1-benzyloxy-3-[(2R,3S)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-3-phenylselanyl-propyl}-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-ol 
• 438002-54-1 (2R,3R,5S,6R)-5-Benzyloxy-2-[(1R,3S)-1-benzyloxy-3-((2R,3S)-2-methoxymethoxymethyl-tetrahydro-pyran-3-yloxy)-3-phenylselanyl-propyl]-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-ol 
• 438002-90-5 (2R,3R,5S,6R)-5-Benzyloxy-2-[(1R,3S)-1-benzyloxy-3-((2R,3S)-2-hydroxymethyl-3,6-dihydro-2H-pyran-3-yloxy)-3-phenylselanyl-propyl]-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-ol 
• 438002-56-3 [(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-((R)-1-benzyloxy-2-(2R,4aR,8aS)-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-2-yl-ethyl)-2-methyl-tetrahydro-pyran-3-yloxy]-triisopropyl-silane 
• 438002-88-1 (2R,3R,5S,6R)-5-Benzyloxy-2-[(1R,3S)-1-benzyloxy-3-((2R,3S)-2-hydroxymethyl-3,6-dihydro-2H-pyran-3-yloxy)-3-phenylsulfanyl-propyl]-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-ol 
• 438002-81-4 (R)-4-Benzyloxy-4-((2R,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-3-hydroxy-2-methyl-tetrahydro-pyran-2-yl)-butane-1,2-diol 
• 438002-80-3 (2R,3R,5S,6R)-5-Benzyloxy-2-((R)-1-benzyloxy-but-3-enyl)-6-benzyloxymethyl-2-methyl-tetrahydro-pyran-3-ol 

Relevant academic research and scientific papers

Synthesis of the FGH ring fragment of ciguatoxin

Stereoselective synthesis of the FGH ring fragment of ciguatoxin is described. The key steps in the present synthesis are an intramolecular radical cyclization to construct oxepane ring G and ring-closing metathesis reaction to construct hexahydrooxonin ring F.