438049-91-3 Usage
Uses
Used in Pharmaceutical Industry:
1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3R,5R)is used as a key intermediate in the preparation of 5HT3 modulators for the treatment of CINV (Chemotherapy-Induced Nausea and Vomiting) and IBS-D (Irritable Bowel Syndrome with Diarrhea). Its unique stereochemistry and structural features make it an important building block in the development of these therapeutic agents.
Additionally, 1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3R,5R)- is used in the preparation of 5-HT2 receptor modulators, which have potential applications in the treatment of various neurological and psychiatric disorders, such as schizophrenia, anxiety, and depression. The selective modulation of 5-HT2 receptors by these agents can help in achieving a balanced therapeutic effect with minimal side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 438049-91-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,8,0,4 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 438049-91:
(8*4)+(7*3)+(6*8)+(5*0)+(4*4)+(3*9)+(2*9)+(1*1)=163
163 % 10 = 3
So 438049-91-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H22N2O2/c1-8-6-13(7-9(2)12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9-/m1/s1
438049-91-3Relevant academic research and scientific papers
2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS
-
Page/Page column 23, (2008/12/04)
Compounds of formulae I, II and III: are disclosed as 5-HT3 inhibitors. The compounds are useful in treating CINV, IBS-D and other diseases and conditions.
