438240-76-7

Upstream product

• 438240-64-3 (S)-2-[((2S,4R)-2-{(S)-3-(1-Benzyl-1H-indol-3-yl)-2-[((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoyl)-methyl-amino]-propionylamino}-4-methyl-octanoyl)-methyl-amino]-propionic acid methyl ester 
• 438240-55-2 3-(1-benzyl-1H-indol-3-yl)-2-[(2-tert-butoxycarbonylamino-4-methyl-pentanoyl)-methyl-amino]-propionic acid methyl ester 
• 237431-25-3 N-<(2S,4R)-2--4-methylheptanoyl>-N-methyl-L-leucine tert-butyl ester 
• 237431-27-5 N-<(2S,4R)-2--4-methylheptanoyl>-N-methyl-L-alanine methyl ester 
• 237431-18-4 N-Boc-PrLeu 
• 42807-86-3 tert-butyl (2S)-4-methyl-2-(methylamino)pentanoate 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 237431-26-4 N-<(2S,4R)-2-amino>-4-methylheptanoyl>-N-methyl-L-leucine tert-butyl ester 

Relevant academic research and scientific papers

Solution-phase parallel synthesis of a pharmacophore library of HUN-7293 analogues: A general chemical mutagenesis approach to defining structure-function properties of naturally occurring cyclic (depsi)peptides

HUN-7293 (1), a naturally occurring cyclic heptadepsipeptide, is a potent inhibitor of cell adhesion molecule expression (VCAM-1, ICAM-1, E-selectin), the overexpression of which is characteristic of chronic inflammatory diseases. Representative of a gene