438244-63-4

Upstream product

• 108-24-7 acetic anhydride 
• 438244-58-7 (2R,3S)-2,3-Bis-(2-chloro-4-methoxy-phenyl)-piperazine 
• 111086-56-7 (1R,2S)/(1S,2R)-1,2-diamino-1,2-bis(2-chloro-4-methoxyphenyl)ethane 

Downstream Products

• 438244-68-9 (2R,3S)-2,3-Bis-(2-chloro-4-methoxy-phenyl)-1,4-diethyl-piperazine 

Relevant academic research and scientific papers

Synthesis, structural evaluation, and estrogen receptor interaction of 2,3-diarylpiperazines

To develop novel estrogen receptor (ER) ligands, ring-fused derivatives of the hormonally active (1R,2S)/(1S,2R)-1-(2-chloro-4-hydroxyphenyl)-2- (2,6-dichloro-4-hydroxyphenyl)ethylenediamine 4b were synthesized. (2R,3S)/(2S,3R)-2-(2-Chloro-4-hydroxyphenyl