438458-90-3Relevant academic research and scientific papers
Improved synthesis of an ethereal tetraamine core for dendrimer construction
Newkome, George R.,Mishra, Amaresh,Moorefield, Charles N.
, p. 3957 - 3960 (2002)
A new route to a pentaerythritol-based tetra-amine is delineated and subsequently contrasted to a previous report. Access to the pure tetraamine is facilitated by the smooth reduction of its tetraazide precusor. Characterization includes the preparation of a 4:1 Zn-tetraphenylporphyrin/tetraamine complex.
Tetrahedral DNA conjugates from pentaerythritol-based polyazides
Ponomarenko, Anna I.,Brylev, Vladimir A.,Sapozhnikova, Ksenia A.,Ustinov, Alexey V.,Prokhorenko, Igor A.,Zatsepin, Timofei S.,Korshun, Vladimir A.
, p. 2386 - 2391 (2016/04/26)
Branching points in DNA nanostructures are usually 3- or 4-way junctions maintained by Watson-Crick non-covalent interactions. However, covalently bound DNA stars could improve the diversity, strength and integrity of DNA nanoscale constructions. We report here the convenient synthesis of 3- and 4-fold pentaerythritol-based azides and their use for the assembly of branched conjugates containing the same or different oligonucleotides (ODNs) and/or fluorescent dyes by stoichiometry controlled copper (I) catalyzed azide alkyne cycloaddition (CuAAC) functionalization.
