438533-40-5Relevant academic research and scientific papers
Efficient catalysis of aqueous Morita-Baylis-Hillman reactions of cyclic enones by a bicyclic imidazolyl alcohol
Gomes, Juliana C.,Rodrigues Jr., Manoel T.,Moyano, Albert,Coelho, Fernando
, p. 6861 - 6866 (2012)
In this paper a new phosphorus-free catalyst for the Morita-Baylis-Hillman reaction is disclosed. A bicyclic imidazolyl alcohol having a Lewis basic center associated with a hydrogen-bond donor group was used as catalyst for the reaction. Aliphatic cycloalkanones such as 2-cyclopentenone and 2-cyclohexanone and aliphatic and aromatic aldehydes were used successfully, and the reaction was found to work nicely using water as solvent in the presence of a phase-transfer additive. Copyright
Design and synthesis of novel cytotoxic agents based on combined framework of quinoline and nimesulide
Reddy, Lingam Venkata,Kethavath, Mohan,Nakka, Mamatha,Beevi, Syed Sultan,Mangamoori, Lakshmi Narasu,Mukkanti, Khagga,Pal, Sarbani
experimental part, p. 80 - 87 (2012/05/05)
Functionalization of quinoline aldehydes, derived from nimesulide framework was carried out using Morita-Baylis-Hillman (MBH) chemistry. A number of novel quinoline-based diverse MBH adducts was prepared via the reaction of derivatives of 2-chloroquinolin
