438533-99-4Relevant academic research and scientific papers
Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit?
Gaukroger, Keira,Hadfield, John A,Lawrence, Nicholas J,Nolan, Steven,McGown, Alan T
, p. 3033 - 3037 (2007/10/03)
A series of combretastatins possessing both a trimethoxy unit and other substituents on ring A has been synthesised and tested for cytotoxicity and their ability to interact with the protein tubulin. All previous studies have indicated that the trimethoxy
