438534-81-7Relevant academic research and scientific papers
Preparation and application for 5-fluorouracil substituted carboxylic acid derivative
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Paragraph 0051; 0052; 0055; 0056, (2018/03/26)
The invention discloses a preparation and an application for a compound compounded from stilbene and diphenylethane antitumor drugs and 5-fluorouracil antitumor drugs. The compound provided by the invention has a general structural formula (I) as describe
A Ramberg-Baecklund route to the stilbenoid anti-cancer agents combretastatin A-4 and DMU-212
Robinson, James E.,Taylor, Richard J. K.
, p. 1617 - 1619 (2008/02/08)
A concise route to combretastatin A-4, a potent inhibitor of tubulin polymerisation, using a Ramberg-Baecklund reaction to form the key (Z)-stilbene unit has been developed; this Ramberg-Baecklund approach has also been extended to prepare the (E)-stilbene DMU-212, which also possesses interesting growth inhibitory properties. The Royal Society of Chemistry.
