438536-02-8Relevant academic research and scientific papers
Regio- and chemoselective C-H chlorination/bromination of electron-deficient arenes by weak coordination and study of relative directing-group abilities
Sun, Xiuyun,Shan, Gang,Sun, Yonghui,Rao, Yu
supporting information, p. 4440 - 4444 (2013/05/22)
It's all relative: A practical and efficient PdII-catalyzed regio- and chemoselective chlorination/bromination has been developed for the facile synthesis of a broad range of aromatic chlorides. The reaction demonstrates excellent reactivity, good functional-group tolerance, and high yields. A preliminary study was conducted to evaluate relative directing-group abilities of various functionalities. Copyright
Direct zincation of functionalized aromatics and heterocycles by using a magnesium base in the presence of ZnCl2
Dong, Zhibing,Clososki, Giuliano C.,Wunderlich, Stefan H.,Unsinn, Andreas,Li, Jinshan,Knochel, Paul
experimental part, p. 457 - 468 (2009/06/24)
A wide range of polyfunctional aryl and heteroaryl zinc reagents were efficiently prepared in THF by using (TMP)2:Mg·2LiCl (TMP = 2,2,6,6-tetramethylpiperamidyl) in the presence of ZnCl2. The possible pathways of this metalation proc
