438566-57-5

Basic information

• Product Name: (3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylethylazetidin-2-one
• Synonyms: (3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylethylazetidin-2-one
• CAS NO: 438566-57-5
• Molecular Weight: 378.514
• Mol File: 438566-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylethylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylethylazetidin-2-one(438566-57-5)
• EPA Substance Registry System: (3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylethylazetidin-2-one(438566-57-5)

Safety Data

• Hazardous Substances Data: 438566-57-5(Hazardous Substances Data)

Upstream product

• 19810-31-2 Benzyloxyacetyl chloride 

Downstream Products

• 199386-10-2 (R)-2,5-dimethyl-3,4-dihydro-2H-pyrrole 1-oxide 

Relevant articles and documents

N,N-dialkylhydrazones as the imine component in the Staudinger-like [2+2] cycloaddition to benzyloxyketene

To overcome the limitations of using unstable imines in Staudinger cycloadditions to ketenes, aldehyde N,N-dialkylhydrazones 1 were used as stable imines. This strategy and a fine tuning of the auxiliary result in a straightforward synthesis of cycloadducts 2, deprotected β-lactams 3, and isoserines 4 (see scheme: a) Et3N, toluene, Δ; b) 1. magnesium monoperoxyphthalate, 2. H2, Pd/C; c) H+).