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2-AMino-5-(3,5-difluorophenyl)pyridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

438585-72-9

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438585-72-9 Usage

Structure

Pyridine derivative with a 2-aminopyridine core and a substituent 3,5-difluorophenyl group

Usage

Building block in the synthesis of pharmaceutical and agrochemical compounds, development of new materials, and research applications

Potential biological activity

Under investigation for medicinal and industrial uses

Check Digit Verification of cas no

The CAS Registry Mumber 438585-72-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,8,5,8 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 438585-72:
(8*4)+(7*3)+(6*8)+(5*5)+(4*8)+(3*5)+(2*7)+(1*2)=189
189 % 10 = 9
So 438585-72-9 is a valid CAS Registry Number.

438585-72-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(3,5-difluorophenyl)pyridin-2-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:438585-72-9 SDS

438585-72-9Relevant academic research and scientific papers

MRGPRX2 ANTAGONISTS AND USES THEREOF

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Paragraph 00215-00216, (2021/05/15)

The present disclosure is directed to use of MrgprX2 antagonists in the treatment of inflammatory disorders, e.g., inflammatory disorders of the skin. This invention is also directed to pharmaceutical compositions comprising a MrgprX2 antagonist and a pharmaceutically or orally acceptable carrier for administration.

Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl Nicotinamides

Majellaro, Maria,Stefanachi, Angela,Tardia, Piero,Vicenti, Chiara,Boccarelli, Angelina,Pannunzio, Alessandra,Campanella, Federica,Coluccia, Mauro,Denora, Nunzio,Leonetti, Francesco,de Candia, Modesto,Altomare, Cosimo Damiano,Cellamare, Saverio

, p. 1380 - 1389 (2017/09/01)

A number of trimethoxybenzoic acid anilides, previously studied as permeability glycoprotein (P-gp) modulators, were screened with the aim of identifying new anticancer agents. One of these compounds, which showed antiproliferative activity against resist

Trimethoxybenzanilide-based P-glycoprotein modulators: An interesting case of lipophilicity tuning by intramolecular hydrogen bonding

Tardia, Piero,Stefanachi, Angela,Niso, Mauro,Stolfa, Diana Antonella,Mangiatordi, Giuseppe Felice,Alberga, Domenico,Nicolotti, Orazio,Lattanzi, Gianluca,Carotti, Angelo,Leonetti, Francesco,Perrone, Roberto,Berardi, Francesco,Azzariti, Amalia,Colabufo, Nicola Antonio,Cellamare, Saverio

, p. 6403 - 6418 (2014/10/16)

One of the principal reasons for the chemotherapy failure is the overexpression of drug efflux pumps, ABCB1 (also known as MDR1 or P-gp) and ABCC1 (also known as MRP1), whose inhibition remains a priority to circumvent drug resistance. We have recently sh

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