438591-75-4Relevant academic research and scientific papers
A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold
Kemp, Melissa M.,Wang, Qiu,Fuller, Jason H.,West, Nathan,Martinez, Nicole M.,Morse, Elizabeth M.,We?wer, Michel,Schreiber, Stuart L.,Bradner, James E.,Koehler, Angela N.
supporting information; experimental part, p. 4164 - 4169 (2011/08/10)
Histone deacetylases (HDACs) are enzymes involved in many important biological functions. They have been linked to a variety of cancers, psychiatric disorders, and other diseases. Since small molecules can serve as probes to study the relevant biological
