439661-92-4Relevant academic research and scientific papers
Crystal structure of 1,7-bis(4-chlorophenyl)-4-(1,3-dithiolan-2-ylidene)-1, 6-heptadiene-3,5-dione
Bubbly,Gudennavar,Verghese, Babu,Viswam, Dhanya,Sudarsanakumar
, p. 641 - 644 (2008)
The synthesis and crystal structure of 1,7-bis(4-chlorophenyl)-4-(1,3- dithiolan-2-ylidene)-1,6-heptadiene-3,5-dione is described. This compound is a curcuminoid analogue, configurationally symmetric about the C4-C5 atoms and also retains the two fold axis in the crystal phase. This compound crystallizes in the space group C2/c with unit cell parameters a = 19.203(1) A, b = 13.147(1) A, c = 8.801(1) A, β = 112.99(1)°, with half a molecule in the asymmetric unit. The ketenedithioacetal functionality present between the carbonyl groups prevents the possibility of keto-enol tautomerization in this compound. The push-pull nature of the ketenedithioacetal functionality organizes the cinnamoyl groups parallel to each other.
Aerobic copper-catalyzed oxidative [6C+1C] annulation: An efficient route to seven-membered carbocycles
Liu, Xiao,Zhang, Lingjuan,Xu, Xianxiu,Wang, Shan,Pan, Ling,Zhang, Qian,Liu, Qun
, p. 8764 - 8767 (2014)
It has been revealed for the first time that co-promoted by CuCl and NaH in the presence of molecular oxygen (air), the reaction of dicinnamoyl ketene dithioacetals as the acyclic C6 synthons with ethyl cyanoacetate gives functionalized seven-membered carbocycles. A mechanism is proposed involving a tandem Michael addition-intramolecular radical cyclization-benzyl C(sp3)-H bond oxidation.
Efficient synthesis of substituted tetrahydrothiopyrano[2,3-b]thiopyran-4, 5-diones by a double annulation strategy from dialkenoylketene dithioacetals
Pan, Wei,Dong, Dewen,Ouyang, Yan,Wu, Rigenhada,Yang, Yang,Liu, Qun
, p. 2115 - 2120 (2008/03/12)
An efficient synthetic procedure for substituted 2,3,6,7- tetrahydrothiopyrano[2,3-b]thiopyran-4,5-diones by a double annulation strategy is described. The ring systems are made in good yields from readily available dialkenoylketene dithioacetals in the p
Facile and clean synthesis of α-alkenoyl ketene-(S,S)-acetals via the aldol condensation reactions in water
Ouyang, Yan,Dong, Dewen,Pan, Wei,Zhang, Jie,Liu, Qun
, p. 10111 - 10116 (2007/10/03)
The aldol condensation reactions of α,α-diacetyl ketene-(S,S)-acetals, 1a and 1b, with aromatic aldehydes 2 in the presence of NaOH in water have been investigated. At room temperature, the base-mediated condensations proceed smoothly to afford the corres
Highly facile and stereoselective intramolecular [2+2]photocycloadditions of bis(alkenoyl)ketenedithioacetals
Joseph, Bubbly K.,Verghese, Babu,Sudarsanakumar,Deepa,Viswam, Dhanya,Chandran, Prakash,Asokan
, p. 736 - 737 (2007/10/03)
The conformational change induced by the introduction of a ketenedithioacetal moiety at C-4 of 1,7-substituted-1,6-heptadiene-3,5-diones results in favorable spatial relationships between the alkenoyl groups to effect efficient intramolecular cycloadditio
