439692-64-5

Basic information

• Product Name: Thieno[2,3-d]pyrimidin-4(1H)-one, 6-(phenylmethyl)-, hydrazone
• CAS NO: 439692-64-5
• Molecular Formula: C13H12N4S
• Molecular Weight: 256.331
• Mol File: 439692-64-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thieno[2,3-d]pyrimidin-4(1H)-one, 6-(phenylmethyl)-, hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-d]pyrimidin-4(1H)-one, 6-(phenylmethyl)-, hydrazone(439692-64-5)
• EPA Substance Registry System: Thieno[2,3-d]pyrimidin-4(1H)-one, 6-(phenylmethyl)-, hydrazone(439692-64-5)

Safety Data

• Hazardous Substances Data: 439692-64-5(Hazardous Substances Data)

Upstream product

• 439692-63-4 C₁₃H₉ClN₂S 

Relevant articles and documents

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure-activity relationships

The synthesis and evaluation of new analogues of thieno[2,3-d]pyrimidin-4-yl hydrazones are described. 2-Pyrdinecarboxaldehyde [6-(tert-butyl)thieno[2,3-d]pyrimidine-4-yl]hydrazone derivatives have been identified as cyclin-dependent kinase 4 (CDK4) inhibitors. The potency, selectivity profile, and structure-activity relationship of this series of compounds are discussed.