439808-07-8

Upstream product

• 1606-75-3 (2-oxoethyl)phosphonic acid diethyl ester 
• 356787-10-5 (2R,3S)-2-(tert-butyldiphenylsilyl)oxy-3,4-epoxy-3-methylbutanal 

Downstream Products

• 439808-08-9 (4E,2S,3R)-7,7-dibromo-3-(tert-butyldiphenylsilyl)oxy-1,2-epoxy-2-methylhepta-4,6-diene 
• 439808-13-6 2-(trimethylsilyl)ethyl (2E,4Z,6E,8R,9S,2'S,3'S)-9,10-epoxy-8-[2'-[(9-fluorenylmethoxy)carbonylamino]-3'-phenylbutanoyloxy]-9-methyldeca-2,4,6-trienoate 
• 439808-14-7 2-(trimethylsilyl)ethyl (2E,4Z,6E,8R,9S,2'S)-9,10-epoxy-8-[2'-[(9-fluorenylmethoxy)carbonylamino]-3'-phenylpropanoyloxy]-9-methyldeca-2,4,6-trienoate 
• 439808-15-8 2-(trimethylsilyl)ethyl (2E,4Z,6E,8R,9S,2'S,3'S)-8-(2'-acetylamino-3'-phenylbutanoyloxy)-9,10-epoxy-9-methyldeca-2,4,6-trienoate 
• 126147-61-3 2-(trimethylsilyl)ethyl (2E,4Z,6E,8R,9S,2'S)-8-(2'-acetylamino-3'-phenylpropanoyloxy)-9,10-epoxy-9-methyldeca-2,4,6-trienoate 
• 439808-09-0 (4E,6Z,2S,3R)-7-bromo-3-(tert-butyldiphenylsilyl)oxy-1,2-epoxy-2-methylhepta-4,6-diene 

Relevant academic research and scientific papers

Asymmetric total synthesis of AK-toxins

A practical total synthesis of AK-toxins (AK-toxin I, 1; II, 2), host-specific toxins against the Japanese pear, has been achieved in 10% total yield, starting from the key intermediate 6. The (2E,4Z,6E)-conjugated triene system was successfully construct