439813-70-4

Basic information

• Product Name: 1H-Pyrrole, 2,5-dihydro-1-(phenylmethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-yl)-
• CAS NO: 439813-70-4
• Molecular Formula: C17H24BNO2
• Molecular Weight: 285.194
• Mol File: 439813-70-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 2,5-dihydro-1-(phenylmethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 2,5-dihydro-1-(phenylmethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-yl)-(439813-70-4)
• EPA Substance Registry System: 1H-Pyrrole, 2,5-dihydro-1-(phenylmethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan- 2-yl)-(439813-70-4)

Safety Data

• Hazardous Substances Data: 439813-70-4(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 439813-69-1 (1,4-dichloro-2-buten-2-yl)boronic acid pinacol ester 

Downstream Products

• 439813-78-2 1-benzyl-3-phenyl-2,5-dihydro-1H-pyrrole 
• 863679-62-3 2-[1-(phenylmethyl)-2,5-dihydro-1H-pyrrol-3-yl]-5-(trifluoromethyl)pyridine 

Relevant articles and documents

USE OF AZABICYCLO HEXANE DERIVATIVES

The present invention provides a new use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate salt thereof, wherein: G is selected from a group consisting of: phenyl, pyridyl, benzothiazolyl, indazolyl; p is an integer ranging from 0 to 5; R1 is independently selected from a group consisting of: halogen, hydroxyl, cyano, C1-4alkyl, haloC1-4alkyl, C1-4 alkoxy, haloC1-4alkoxy, C1-4alkanoyl; or corresponds to a group R5; R2 is hydrogen or C1-4 alkyl; R3 I s C1-4alkyl; R4 is hydrogen, or a phenyl group, a heterocyclyl group, a 5- or 6-membered heteroaromatic group, or a 8- to 11-membered bicyclic group, any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; R5 is a moiety selected from the group consisting of: isoxazolyl, -CH2-N-pyrrolyl, 1,1-dioxido-2-isothiazolidinyl, thienyl, thiazolyl, pyridyl, 2-pyrrolidinonyl, and such a group is optionally substituted by one or two substituents selected from: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; and when R1 is chlorine and p is 1, such R1 is not present in the ortho position with respect to the linking bond to the rest of the molecule; and when R1 corresponds to R5, p is 1; in the manufacture of a medicament for the treatment of a somatoform disorder such as body dysmorphic disorder or hyperchondriasis, bulimia nervosa, anorexia nervosa, binge eating, paraphilia and nonparaphilic sexual addictions, Sydeham's chorea, torticollis, autism, a movement disorder including Tourette's syndrome; and in the manufacture of a medicament for the treatment of premature ejaculation.

Suzuki coupling reactions in heterocyclic chemistry: Synthesis of 3-substituted pyrrolines and pyrroles

A simple preparation of N-substituted 3-pyrroline boromic esters from primary amines is described. The Suzuki-Miyaura coupling of these heterocycles with aryl halides proceeds in good yields. Alternatively, oxidation with DDQ or MnO2, gives the