439867-52-4

Upstream product

• 439867-50-2 (S)-3-[2-((1S,3S)-1-Allyl-3,7-dimethyl-oct-6-enyloxy)-acetyl]-4-isopropyl-oxazolidin-2-one 
• 439867-65-9 ((1S,3S)-1-Allyl-3,7-dimethyl-oct-6-enyloxy)-acetic acid 
• 170807-72-4 6,10-dimethyl-undeca-1,9-dien-4-ol 

Downstream Products

• 439867-55-7 (S)-5-{(2R,6R)-6-[(Z)-4-(4-Methoxy-benzyloxy)-but-2-enyl]-3,6-dihydro-2H-pyran-2-yl}-4-methyl-2-methylene-pentan-1-ol 
• 439867-54-6 (2R,6R)-2-((S)-2,6-Dimethyl-hept-5-enyl)-6-[(Z)-4-(4-methoxy-benzyloxy)-but-2-enyl]-3,6-dihydro-2H-pyran 
• 439867-67-1 (S)-5-{(2R,6R)-6-[(Z)-4-(4-Methoxy-benzyloxy)-but-2-enyl]-3,6-dihydro-2H-pyran-2-yl}-4-methyl-2-methylene-pentanal 
• 439867-53-5 1-[(Z)-(R)-5-((1S,3S)-1-Allyl-3,7-dimethyl-oct-6-enyloxy)-hepta-2,6-dienyloxymethyl]-4-methoxy-benzene 

Relevant academic research and scientific papers

Asymmetric total synthesis of (-)-laulimalide: Exploiting the asymmetric glycolate alkylation reaction

A concise total synthesis of the potent antitumor macrolide (-)-laulimalide is described. The observation that homoallylic (or latent homoallylic) C-O bonds are present at C5, C9, C15, C19, and C23 led to the strategic decision to rely heavily on the asym