439919-49-0Relevant academic research and scientific papers
Orally active PDE4 inhibitor with therapeutic potential
Ochiai, Hiroshi,Ohtani, Tazumi,Ishida, Akiharu,Kishikawa, Katuya,Yamamoto, Susumu,Takeda, Hiroshi,Obata, Takaaki,Nakai, Hisao,Toda, Masaaki
, p. 555 - 571 (2004)
Based on the promising results obtained by the clinical trial of Ariflo, further optimization of the spatial arrangement of the three pharmacophores (the carboxylic acid moiety, nitrile moiety and 3-cyclopentyloxy-4-methoxyphenyl moiety) in the
