440-54-0 Usage
Uses
Used in Pharmaceutical Industry:
[1,2,4]triazolo[3,4-a]isoquinoline is used as a key component in the development of new pharmaceuticals for the treatment of various diseases. Its unique structure and properties make it a versatile platform for drug discovery and development.
Used in Agrochemical Industry:
In the agrochemical industry, [1,2,4]triazolo[3,4-a]isoquinoline is used as a building block for the creation of novel compounds with potential applications in pest control and crop protection.
Used in Material Science:
[1,2,4]triazolo[3,4-a]isoquinoline is also utilized in material science for the development of new materials with specific properties, such as improved stability or reactivity, due to its unique chemical structure.
Used in Cancer Treatment Research:
[1,2,4]triazolo[3,4-a]isoquinoline derivatives have been studied for their potential use in the treatment of various types of cancer, showcasing their potential as therapeutic agents in oncology.
Used in Neurological Disorder Treatment Research:
[1,2,4]triazolo[3,4-a]isoquinoline and its derivatives are also being investigated for their potential applications in the treatment of neurological disorders, given their biological activity and structural versatility.
Used in Infectious Disease Treatment Research:
Furthermore, [1,2,4]triazolo[3,4-a]isoquinoline has been explored for its potential role in the development of treatments for infectious diseases, highlighting its broad-spectrum applicability in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 440-54-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 440-54:
(5*4)+(4*4)+(3*0)+(2*5)+(1*4)=50
50 % 10 = 0
So 440-54-0 is a valid CAS Registry Number.
440-54-0Relevant academic research and scientific papers
Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source
Liu, Lingfeng,Qiao, Chunhua,Shen, Bei,Xu, Yiwen
, (2020/04/01)
1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.
