4401-19-8

Upstream product

• 38287-47-7 7-cycloheptatrienyl-acetaldehyde 
• 4480-98-2 2-cycloheptylethanol 
• 14224-70-5 methyl 2-cycloheptylacetate 
• 4401-20-1 2-cycloheptylacetic acid 

Downstream Products

• 1026245-40-8 4-acetyl-1-benzyl-3-cycloheptylmethyl-2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[e][1,4]diazonine-5-carboxylic acid benzyl ester 
• 196948-99-9 4-acetyl-1-benzyl-3-cycloheptylmethyl-2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[e][1,4]diazonine-5-carboxylic acid 

Relevant academic research and scientific papers

ASPARAGINE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of them, pharmaceutical compositions comprising them, methods of preparation thereof, intermediate compounds useful for the preparation thereof, and methods of treatment or prophylaxis of diseases, in particular cancer, such as colorectal cancer, using these. (A) (I)

N-ARYL PYRAZOLES AS NRF2 REGULATORS

The present invention relates to N-aryl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators. In particular, the compounds of this invention include a compound of Formula (I).

BIARYL PYRAZOLES AS NRF2 REGULATORS

The present invention relates to biaryl pyrazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.

NRF2 REGULATORS

Provided are aryl analogs，pharmaceutical compositions containing them and their use as NRF2 regulators.